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Multifocal electroretinogram in non-pathological myopic subjects: correlation with optical coherence tomography
- Source :
- International Journal of Ophthalmology, Vol 9, Iss 2, Pp 286-291 (2016)
- Publication Year :
- 2014
-
Abstract
- AIM: To investigate the changes of retinal function in non-pathological myopic subjects using multifocal electroretinography (mfERG) and to correlate the data with the central macular thickness obtained using optical coherence tomography (OCT). METHODS: One hundred and thirteen subjects (113 eyes) with age range from 18 to 35y were enrolled in the study. The subjects were divided into four groups according to spherical equivalent (SE) and axial length (AL): emmetropia group (EG, n=31; SE: +0.75 to -0.50 D; AL: 22 to 24 mm), low and medium myopia group (LMMG, n=26; SE: >-0.50 to -6.00 D; AL: >24 to 26 mm), high myopia group (HMG, n=34; SE: >-6.00 to -10.00 D; AL: >26 to 28 mm) and super high myopia group (SHMG, n=22; SE: >-10.00 D; AL:>28 mm). The P1 amplitude density, P1 amplitude, and P1 implicit time of the first-order kernel mfERG responses were obtained and grouped into five rings. The central subfield macular thickness (CST) was obtained using macular cube 512×218 scan of Cirrus HD-OCT. RESULTS: With the increasing of eccentricity, the first positive peak (P1) amplitude density (P=0.0000, 0.0001, 0.0021 in ring 1-3 respectively) and P1 amplitude (all P=0.0000 in ring 1-5) of each group decreased. With the increasing of myopia, P1 implicit time gradually extended (all P=0.0000 in ring 1-3). The average CST in four diagnostic groups was 241.56±12.72 μm, 244.56±12.19 μm, 254.33±11.61 μm, 261.75±11.83 μm respectively. With the increasing of myopia, CST increased (P
- Subjects :
- medicine.medical_specialty
Emmetropia
Correlation
03 medical and health sciences
0302 clinical medicine
Optical coherence tomography
lcsh:Ophthalmology
Clinical Research
Ophthalmology
medicine
myopia
Pathological
optical coherence tomography
medicine.diagnostic_test
business.industry
High myopia
Amplitude
lcsh:RE1-994
030221 ophthalmology & optometry
Multifocal electroretinography
Positive relationship
Optometry
multifocal electroretinogram
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 22223959
- Volume :
- 9
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- International journal of ophthalmology
- Accession number :
- edsair.doi.dedup.....c4ababc583d150d968755647013ce70a