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DBS in Treatment of Post-Traumatic Stress Disorder
- Source :
- Brain Sciences, Vol 8, Iss 1, p 18 (2018), Brain Sciences
- Publication Year :
- 2017
- Publisher :
- Preprints, 2017.
-
Abstract
- Background: Post-traumatic stress disorder (PTSD) is a common debilitating psychiatric condition for which pharmacological therapy is not always solvable. Various treatments have been suggested for these patients. Deep brain stimulation (DBS) is currently under investigation for patients affected by PTSD. 2) Methods: We review the neurocircuitry and up to date clinical concepts that may be of relevance for the implementation of DBS in posttraumatic stress disorder (PTSD). 3) Results: The role of DBS in treatment-refractory PTSD patients has been investigated relying on both preclinical and clinical studies. 4) Conclusions: DBS for PTSD is in its preliminary phases and likely to provide hope to patients with medical refractory PTSD following the results of randomized controlled studies.
- Subjects :
- Oncology
medicine.medical_specialty
Deep brain stimulation
Pharmacological therapy
medicine.medical_treatment
Review
Controlled studies
Amygdala
behavioral disciplines and activities
lcsh:RC321-571
medicine_pharmacology_other
03 medical and health sciences
0302 clinical medicine
Physical medicine and rehabilitation
Refractory
Internal medicine
mental disorders
medicine
Prefrontal cortex
lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry
prefrontal cortex
business.industry
General Neuroscience
Traumatic stress
amygdala
030227 psychiatry
deep brain stimulation
fear extinction
Posttraumatic stress
medicine.anatomical_structure
surgical procedures, operative
posttraumatic stress disorder
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Brain Sciences, Vol 8, Iss 1, p 18 (2018), Brain Sciences
- Accession number :
- edsair.doi.dedup.....c46178ec0786601111e26744ce8670ae