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DBS in Treatment of Post-Traumatic Stress Disorder

Authors :
Angelo Lavano
Giorgio Volpentesta
Serena Marianna Lavano
Giusy Guzzi
Raffaele Tiriolo
Attilio Della Torre
Source :
Brain Sciences, Vol 8, Iss 1, p 18 (2018), Brain Sciences
Publication Year :
2017
Publisher :
Preprints, 2017.

Abstract

Background: Post-traumatic stress disorder (PTSD) is a common debilitating psychiatric condition for which pharmacological therapy is not always solvable. Various treatments have been suggested for these patients. Deep brain stimulation (DBS) is currently under investigation for patients affected by PTSD. 2) Methods: We review the neurocircuitry and up to date clinical concepts that may be of relevance for the implementation of DBS in posttraumatic stress disorder (PTSD). 3) Results: The role of DBS in treatment-refractory PTSD patients has been investigated relying on both preclinical and clinical studies. 4) Conclusions: DBS for PTSD is in its preliminary phases and likely to provide hope to patients with medical refractory PTSD following the results of randomized controlled studies.

Details

Language :
English
Database :
OpenAIRE
Journal :
Brain Sciences, Vol 8, Iss 1, p 18 (2018), Brain Sciences
Accession number :
edsair.doi.dedup.....c46178ec0786601111e26744ce8670ae