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Influence of confounding factors on plasma Mid-Regional pro-Adrenomedullin and Mid-Regional pro-A-type Natriuretic Peptide concentrations in healthy individuals
- Source :
- Biomarkers. 16:281-287
- Publication Year :
- 2011
- Publisher :
- Informa UK Limited, 2011.
-
Abstract
- Background: MRproADM and MRproANP can be used as diagnostic and prognostic markers in heart failure.Aim: The objective was to identify confounding factors for the interpretation of plasma MRproADM and MRproANP concentrations.Methods: A total of 518 healthy volunteers with a mean age of 60.84 ± 7.41 years were analyzed. We evaluated the influence of demographic factors, renal function and echocardiographic indices on the candidate peptides.Results: Multivariate analysis revealed that age (P
- Subjects :
- Male
medicine.medical_specialty
Multivariate analysis
Confounding Factors (Epidemiology)
Health, Toxicology and Mutagenesis
Clinical Biochemistry
Renal function
Biochemistry
Gastroenterology
Adrenomedullin
Internal medicine
Heart rate
medicine
Humans
Protein Precursors
Aged
business.industry
Confounding
Confounding Factors, Epidemiologic
Middle Aged
medicine.disease
Endocrinology
Heart failure
Multivariate Analysis
Female
business
Body mass index
Atrial Natriuretic Factor
Subjects
Details
- ISSN :
- 13665804 and 1354750X
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- Biomarkers
- Accession number :
- edsair.doi.dedup.....c43d0a385b2ca5026e793b074fe6b67a