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Posterior reversible encephalopathy syndrome (PRES) and CT perfusion changes

Posterior reversible encephalopathy syndrome (PRES) and CT perfusion changes

Authors :
Arash Salardini
Vishnumurthy Shushrutha Hedna
Ajay Kumar Pandey
Latha G. Stead
Het Patel
Sharathchandra Bidari
Christopher G. Favilla
Aunali S. Khaku
Akhil Patel
Amareshwari Gottipati
Diana Mora
Michael F. Waters
Source :
International Journal of Emergency Medicine
Publication Year :
2012
Publisher :
Springer Science and Business Media LLC, 2012.

Abstract

Posterior reversible encephalopathy syndrome (PRES) can present with focal neurologic deficits, mimicking a stroke and can often represent a diagnostic challenge when presenting atypically. A high degree of suspicion is required in the clinical setting in order to yield the diagnosis. Cerebral CT perfusion (CTP) is utilized in many institutions as the first line in acute stroke imaging. CTP has proved to be a very sensitive measure of cerebral blood flow dynamics, most commonly employed to delineate the infarcted tissue from penumbra (at-risk tissue) in ischemic strokes. But abnormal CTP is also seen in stroke mimics such as seizures, hypoglycemia, tumors, migraines and PRES. In this article we describe a case of PRES in an elderly bone marrow transplant recipient who presented with focal neurological deficits concerning for a cerebrovascular accident. CTP played a pivotal role in the diagnosis and initiation of appropriate management. We also briefly discuss the pathophysiology of PRES.

Details

ISSN :
18651380
Volume :
5
Database :
OpenAIRE
Journal :
International Journal of Emergency Medicine
Accession number :
edsair.doi.dedup.....c40bdb8fce89f9c464a1492023dc6f51
Full Text :
https://doi.org/10.1186/1865-1380-5-12