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Cholesterol synthesis and metabolism as a function of unpredictable shock stimulation
- Source :
- Physiologybehavior. 11(1)
- Publication Year :
- 1973
-
Abstract
- Rats fed a high lipid diet and also exposed to unavoidable and unpredictable grid shock for 2 and 8 days showed higher levels of accumulated chemical cholesterol in aorta, kidney, liver and serum as compared to control rats fed only the high lipid diet. Thirty days of shock stress produced similar results except that kidney tissue revealed lower and nonsignificant levels of accumulated cholesterol. A differential cholesterol clearing mechanism for the various tissues is postulated to explain the relative vulnerability of aorta, liver and kidney to stress-induced cholesterol deposition.
- Subjects :
- Male
medicine.medical_specialty
Arteriosclerosis
Experimental and Cognitive Psychology
Stimulation
Biology
Cholesterol deposition
Kidney
Behavioral Neuroscience
chemistry.chemical_compound
Internal medicine
medicine.artery
medicine
Animals
Humans
Aorta
Carbon Isotopes
Electroshock
Cholesterol
Body Weight
Metabolism
Rats
Disease Models, Animal
medicine.anatomical_structure
Endocrinology
chemistry
Liver
Shock (circulatory)
lipids (amino acids, peptides, and proteins)
medicine.symptom
Function (biology)
Stress, Psychological
Subjects
Details
- ISSN :
- 00319384
- Volume :
- 11
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Physiologybehavior
- Accession number :
- edsair.doi.dedup.....c3f7484c61788aa28135612db91e866f