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Study on Closure of Skull Base Defect Post-Endoscopic Endonasal Transsphenoid Pituitary Surgery: A Novel Flap Design
- Source :
- J Neurol Surg B Skull Base
- Publication Year :
- 2019
-
Abstract
- Objective This study was aimed to compare the closure of skull base defect in endoscopic endonasal transsphenoid surgery of pituitary tumors, using bipedicled nasal septal flap versus fascial closure. The study hypothesis being that bipedicled nasal septal flap is better, compared with fascial closure of skull base defect post–endoscopic endonasal transsphenoid surgery of pituitary tumors. Methods All the eligible patients were randomly divided into two groups and then randomly allocated to the surgeons. In one group, fat and fascia lata was used for closure of the skull base defect and nasal septal flap was not harvested whereas in the other, nasal septal flap was used for closure. Results There was a statistically significant difference in postoperative cerebrospinal fluid leak between the two groups. Patients who had undergone flap repair had lower incidence of postoperative cerebrospinal fluid (CSF) leak. Duration of postoperative hospital stay was also less among the group who underwent flap repair (statistically significant). Conclusion Bipedicled nasal septal flap serves an excellent cover for the skull base defect following endoscopic endonasal transsphenoidal pituitary surgery. It can prevent postoperative CSF leak even in cases where tissue glue is not used.
- Subjects :
- medicine.medical_specialty
Leak
business.industry
Pituitary tumors
medicine.disease
Flap repair
Surgery
03 medical and health sciences
Skull
0302 clinical medicine
Cerebrospinal fluid
medicine.anatomical_structure
Fascia lata
medicine
Nasal septum
otorhinolaryngologic diseases
Neurology (clinical)
030223 otorhinolaryngology
Pituitary surgery
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 21936331
- Volume :
- 82
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of neurological surgery. Part B, Skull base
- Accession number :
- edsair.doi.dedup.....c3dc4a3d6865ae379a6e2f063d945a9f