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K-doped ZnO nanostructures: biosynthesis and parasiticidal application
- Source :
- Journal of Materials Research and Technology, Vol 15, Iss, Pp 5445-5451 (2021)
- Publication Year :
- 2021
- Publisher :
- Elsevier, 2021.
-
Abstract
- In general, the growing resistance to traditional anti-leishmaniasis drugs and the ineffectiveness of appropriate treatment for leishmaniasis have prompted researchers to investigate the antiparasitic properties of plant-mediated synthesized nanomaterials and nanosystems. Potassium (K)-doped zinc oxide (ZnO) nanostructures with unique physicochemical properties can be employed as attractive candidate against this parasitic disease. In this study, K-doped zinc oxide (KdZ) nanoparticles (NPs) were synthesized using Artemisia annua extracts via an eco-friendly method with the advantages of simplicity, low cost, and up-scalability. A. annua extracts were deployed due to their antiparasitic effects. The synthesized NPs were characterized by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and transmission electron microscopy (TEM). The toxicity of these nanostructures was evaluated on Leishmania tropica and normal macrophage cells. As a result, the K-doped ZnO NPs could inhibit the L. tropica cells growth, in vitro.
- Subjects :
- Leishmania tropica
Materials science
Antiparasitic
medicine.drug_class
Scanning electron microscope
Artemisia annua
Nanoparticle
chemistry.chemical_element
Zinc
Nanomaterials
Biomaterials
Green synthesis
parasitic diseases
medicine
Mining engineering. Metallurgy
biology
Metals and Alloys
technology, industry, and agriculture
TN1-997
biology.organism_classification
Surfaces, Coatings and Films
chemistry
Transmission electron microscopy
K-doped ZnO nanoparticles
Ceramics and Composites
Nuclear chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 22387854
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Journal of Materials Research and Technology
- Accession number :
- edsair.doi.dedup.....c3d76979611b5b3af0bd82a0423339f4