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Critical analysis of cystic echinococcosis control programs and praziquantel use in South America, 1974-2010
- Source :
- Revista panamericana de salud publica = Pan American journal of public health. 31(1)
- Publication Year :
- 2010
-
Abstract
- Cystic echinococcosis (CE) is one of the most prevalent zoonoses in Argentina, Brazil, Chile, Peru, and Uruguay. Control programs in South America were originally modeled after programs developed in insular territories, such as Tasmania and New Zealand. The advent and proven effectiveness of praziquantel, plus the experience of insular models, produced high expectations for rapid advances; however, after 30 years of praziquantel use, no endemic area in South America has obtained eradication. In fact, only modest gains in CE control have been made and impact on prevalence among humans has been slight. A major impediment has been the infrastructure needed to administer praziquantel to dogs in rural areas 8 times per year over numerous years, a requirement for rapid attack stage 1. Such an infrastructure has not been financially or politically sustainable in endemic areas, which tend to be the poorest. On the other hand, certain areas in Argentina have had success with simple and economically viable alternatives. Based primarily on continuous field work supported by the local community, these strategies have significantly decreased transmission to humans, the health sector's main objective. In addition, new possibilities and tools, such as the EG95 vaccine, are being evaluated; as are early detection and treatment of asymptomatic carriers.
- Subjects :
- Program evaluation
Adolescent
Sheep Diseases
Rural Health
Praziquantel
law.invention
Dogs
law
Echinococcosis
Zoonoses
parasitic diseases
Preventive Health Services
medicine
Animals
Humans
Dog Diseases
Socioeconomics
Child
Retrospective Studies
Anthelmintics
Infection Control
Vaccines
Sheep
Rural health
Incidence
Vaccination
Public Health, Environmental and Occupational Health
Epidemiologic Surveillance
Helminth Proteins
South America
medicine.disease
Drug Utilization
Local community
Geography
Transmission (mechanics)
Antigens, Helminth
Population Surveillance
Asymptomatic Diseases
Carrier State
Rural area
medicine.drug
Forecasting
Program Evaluation
Subjects
Details
- ISSN :
- 16805348
- Volume :
- 31
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Revista panamericana de salud publica = Pan American journal of public health
- Accession number :
- edsair.doi.dedup.....c3be06e0f910dd725ef3ad09c0b952e8