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Associations of fermented and non-fermented dairy consumption with serum C-reactive protein concentrations – A cross-sectional analysis
- Source :
- Clinical Nutrition ESPEN. 48:401-407
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- The results of epidemiological studies on dairy products and low-grade inflammation are scarce and inconsistent. Some studies have suggested that the associations may vary depending on the type of dairy product consumed. The aim of this cross-sectional study was to investigate the associations between intake of fermented and non-fermented dairy products and separately butter and serum high-sensitivity C-reactive protein (hs-CRP), a common inflammation marker, among a population with high dairy intake.The study included 1338 generally healthy men aged 42-60 years and serum hs-CRP ≤10 mg/L from the Kuopio Ischaemic Heart Disease Risk Factory Study, examined in 1984-1989. Dietary intakes were assessed using 4-day food records. ANCOVA and linear and logistic regression were used for analyses.The reported mean intakes of fermented and non-fermented dairy products and butter were 189 (SD 217), 522 (SD 330) and 33 (SD 27) g/d, respectively. In the model adjusted for age, year of examination and energy intake (Model 1), higher intake of total dairy, total non-fermented dairy, total milk and butter were associated with higher concentration of serum hs-CRP, whereas fermented dairy intake was not associated with serum hs-CRP. After further adjustment for potential confounders, only higher butter intake remained statistically significantly associated with increased serum hs-CRP (P-trend = 0.049). The odds ratio for elevated hs-CRP (3 mg/L) in the highest vs. the lowest quartile was 2.50 (95% confidence interval 1.19-5.26, P-trend = 0.02).These results suggest that high intake of butter, but not other dairy products may be associated with increased low-grade inflammation.
Details
- ISSN :
- 24054577
- Volume :
- 48
- Database :
- OpenAIRE
- Journal :
- Clinical Nutrition ESPEN
- Accession number :
- edsair.doi.dedup.....c3aab62c89db74d31dfae179c6d0fce8