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Tongue thickness evaluation using ultrasonography can predict swallowing function in amyotrophic lateral sclerosis patients
Tongue thickness evaluation using ultrasonography can predict swallowing function in amyotrophic lateral sclerosis patients
- Source :
- Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 127(2)
- Publication Year :
- 2015
-
Abstract
- Objective Dysphagia is a critical issue in amyotrophic lateral sclerosis (ALS) patients. An evaluation of swallowing function is important for assessing the risk of aspiration. We investigated the validity of tongue sonography compared with videofluoroscopic examination for ALS patients. Methods We investigated 18 ALS patients. Nine subjects underwent repeated investigations. All of the subjects underwent tongue sonography and videofluoroscopic examination. Additionally, tongue sonography was evaluated in 18 age- and sex-matched healthy volunteers. To determine tongue thickness, we measured the vertical distance from the surface of the mylohyoid muscle to the tongue dorsum using ultrasonography. Results In the ALS patients, the tongue was significantly thinner than in healthy subjects. Tongue thickness was associated with body mass index and onset type in the ALS patients ( p =0.006). Temporal analyses of videofluoroscopy revealed that tongue thickness was associated with oral preparatory and transit time ( p =0.032) but not with pharyngeal transit time. Repeated measurement data revealed a decrease in tongue thickness over the course of the measurements ( p =0.002). Conclusions In ALS patients, reduced tongue thickness suggests disease progression and tongue dysfunction. Significance Tongue sonography is a useful modality for the non-invasive and quantitative evaluation of tongue thickness and dysphagia in ALS patients.
- Subjects :
- Male
medicine.medical_specialty
Severity of Illness Index
03 medical and health sciences
0302 clinical medicine
Swallowing
Tongue
Predictive Value of Tests
Physiology (medical)
Severity of illness
medicine
Humans
Amyotrophic lateral sclerosis
Aged
Ultrasonography
business.industry
Amyotrophic Lateral Sclerosis
030206 dentistry
Middle Aged
medicine.disease
Dysphagia
Sensory Systems
Surgery
Deglutition
medicine.anatomical_structure
Neurology
Predictive value of tests
Mylohyoid muscle
Disease Progression
Female
Neurology (clinical)
Radiology
medicine.symptom
business
Deglutition Disorders
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 18728952
- Volume :
- 127
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
- Accession number :
- edsair.doi.dedup.....c370298de4cb5dcb438d4b2ffa34354b