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Improvement of Survival Rate in Patients with Cardiogenic Shock by Using Nonpulsatile and Pulsatile Ventricular Assist Device
- Source :
- The International Journal of Artificial Organs. 15:715-721
- Publication Year :
- 1992
- Publisher :
- SAGE Publications, 1992.
-
Abstract
- Between January 1988 and January 1992, 65 patients (pts) had a ventricle assist device (VAD) inserted in our clinic. In 24 pts a VAD was applied because of primarily unsuccessful weaning from cardiopulmonary bypass (Group A). In a further 24 pts (Group B) a VAD was installed for the therapy of refractive cardiogenic shock (CS) after initially successful cardiac surgery (n=21) and after acute myocardial infarction (n=3). Twelve pts were bridged to heart transplantation (Group C) and five had a VAD inserted for various other reasons (Group D). In 36 (55.4%) of the total 65 pts a nonpulsatile VAD (Biomedicus® 540) was used: 10 in Group A; 20 in B, 3 in C and 3 in D. In 29 pts (44.6%) a pulsatile VAD (Abiomed® BVS 5000) was used: 14 in Group A, 4 in B, 9 in C and 2 in D. Weaning rate and long-term survival rates were 50% and 46% respectively in Group A and 38% and 42% in Group B. Seven pts from Group C were transplanted and six are long-term survivors. Two pts (40%) in Group D were discharged from hospital. Major postoperative complications were bleeding (46%), thromboembolism (14%), multiple organ failure (11%), renal failure (11%), arterial embolism (4.6%), sepsis (3%). The results indicate that application of a VAD can be recommended in pts with postcardiotomy CS to allow recovery of cardiac function and in pts with irreversible ventricular damage as bridging to HTX.
- Subjects :
- Adult
Male
medicine.medical_specialty
Arterial embolism
Epinephrine
Dopamine
medicine.medical_treatment
Shock, Cardiogenic
030232 urology & nephrology
Biomedical Engineering
Medicine (miscellaneous)
Bioengineering
macromolecular substances
030204 cardiovascular system & hematology
law.invention
Biomaterials
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
law
Internal medicine
otorhinolaryngologic diseases
medicine
Cardiopulmonary bypass
Humans
Myocardial infarction
Survival rate
Aged
Aged, 80 and over
Heart transplantation
business.industry
Cardiogenic shock
General Medicine
Middle Aged
medicine.disease
Cardiac surgery
Survival Rate
Ventricular assist device
Cardiology
Heart Transplantation
Female
Heart-Assist Devices
business
Subjects
Details
- ISSN :
- 17246040 and 03913988
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- The International Journal of Artificial Organs
- Accession number :
- edsair.doi.dedup.....c35a106baaee86ca6348bd450f8ab46e