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Primary Leiomyosarcoma of Peritoneal Cavity
- Source :
- Rare Tumors, Rare Tumors, Vol 6, Iss 1 (2014)
- Publication Year :
- 2014
- Publisher :
- PAGEPress Publications, Pavia, Italy, 2014.
-
Abstract
- Leiomyosarcomas of soft tissue are the rare tumors and the retroperitoneum is the most common site involved. We report a case of primary leiomyosarcoma of the peritoneal cavity which clinically presented with suprapubic, freely mobile, nontender mass which measured 10×10 cm in size. Contrast enhanced computed tomography revealed well defined heterogenous hypodense solid cystic mass. The mass was surgically excised out in its entirety. The histopathological examination revealed spindle cells arranged in alternating fascicles having pleomorphic nuclei, indistinct margin and eosinophilic cytoplasm with foci of haemorrhage, necrosis and 5-6 mitosis/HPF. The spindle cells were immunoreactive for smooth muscle actin, desmin and negative for S-100, CD-34 and c-kit. Histopathology and immunohistochemistry were helpful in making the final confirmatory diagnosis. Leiomyosarcomas are aggressive tumors, with poor prognosis and often difficult to treat. The survival rates are lowest among all soft tissue sarcomas.
- Subjects :
- medicine.medical_specialty
Pathology
tumor
Histology
sarcoma
business.industry
Soft tissue
Case Report
medicine.disease
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
lcsh:RC254-282
body regions
Peritoneal cavity
medicine.anatomical_structure
Oncology
tumor, sarcoma, soft tissue
Primary Leiomyosarcoma
Eosinophilic
medicine
Immunohistochemistry
Histopathology
Desmin
Sarcoma
business
soft tissue
Subjects
Details
- Language :
- English
- ISSN :
- 20363613 and 20363605
- Volume :
- 6
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Rare Tumors
- Accession number :
- edsair.doi.dedup.....c3230ac26ced69fedbde038f63e5a6ed