Bisphosphonates are associated with the development of exposed bone (osteonecrosis/osteopetrosis) in the oral cavity

Article Title and Bibliographic Information Bisphosphonates-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention and treatment. Marx RE, Sawatary Y, Fortin M, Broumand V. J Oral Maxillofac Surg 2005;63:1567-75. Level of Evidence 4 Purpose/Question To determine type, dosage, and duration of bisphosphonate therapy; indication of use; clinical findings; comorbidities present; and the event that initiated the bone exposure. Source of Funding None disclosed Type of Study/Design Retrospective case series review