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Gamma probe-guided surgery for revision thyroidectomy: in comparison with conventional technique
- Source :
- Journal of endocrinological investigation. 28(7)
- Publication Year :
- 2005
-
Abstract
- Reoperative thyroid surgery may be required in patients who undergo any procedure less than total or near total thyroidectomy. The aim of this study was to investigate advantages of gamma-probe guided revision thyroidectomy (GGRT) over conventional revision thyroidectomy (CRT) in patients with differentiated thyroid carcinoma (DTC). GGRT was assessed according to the TSH values, complication rates and the incidence of carcinoma in residual thyroid tissue. In this randomised prospective clinical trial, 25 patients with differentiated thyroid carcinoma who had previously undergone surgery for benign multinodular goiter were included in the study. GGRT was performed in 11 (44%) patients (Group 1) and CRT in 14 (65%) (Group 2). The intraoperative mean ratio of thyroid activity to background activity (T/B) was detected as 5.1 +/- 1.4 and the mean ratio of thyroid bed activity to background activity after excision (Tbed/B) was 1.3 +/- 0.3, (p0.01). Although the incidence of carcinoma in residual thyroid tissue was higher in group 1 (4/11) in comparison to group 2 (1/14), it was not statistically significant. The elevation of the TSH concentration at the first post-operative month was significantly higher in group 1 in comparison with group 2 (18 +/- 25 5 +/- 3 mlU/l), (p0.02). These results indicate that intraoperative gamma probe application may be beneficial to detect and remove residual thyroid tissue in revision thyroidectomy.
- Subjects :
- Adult
Male
Reoperation
endocrine system
medicine.medical_specialty
endocrine system diseases
Endocrinology, Diabetes and Metabolism
Thyroid Gland
Thyrotropin
Thyroid carcinoma
Endocrinology
medicine
Carcinoma
Humans
Prospective Studies
Thyroid Neoplasms
Radionuclide Imaging
business.industry
Incidence (epidemiology)
Thyroid
Technetium
Middle Aged
Revision thyroidectomy
medicine.disease
Prognosis
Surgery
Clinical trial
medicine.anatomical_structure
Treatment Outcome
Thyroidectomy
Female
business
Complication
Gamma probe
Goiter, Nodular
Subjects
Details
- ISSN :
- 03914097
- Volume :
- 28
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Journal of endocrinological investigation
- Accession number :
- edsair.doi.dedup.....c2d6b3601c1bad6672eb6bd0dfbff113