Additional file 1 of Non-CpG sites preference in G:C > A:T transition of TP53 in gastric cancer of Eastern Europe (Poland, Romania and Hungary) compared to East Asian countries (China and Japan)

Additional file 1: Supplementary Figure S1. Localization of TP53 mutations at CpG and non-CpG sites in GC samples from Eastern Europe, China, and Japan (exon 4-8). Mutation-distribution maps were created using the cBioPortal mutation mapper ( http://www.cbioportal.org/mutation_mapper ). Black dots indicate truncating mutations (nonsense and frameshift mutations). The light purple dot indicates a silent mutation. P53_TAD, TP53 transcriptional activation domain; P53, TP53 DNA-binding domain; P53 tetramer, TP53 tetramer domain.