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Multivariate prognostic study on node-positive gastric cancer: is tumor size a prognostic indicator?
- Source :
- Hepato-gastroenterology. 59(114)
- Publication Year :
- 2011
-
Abstract
- BACKGROUND/AIMS We analyzed the clinicopathological factors of patients with node-positive gastric cancer, evaluated the prognostic factors associated with long-term survival and clarified the effect of tumor size on long-term survival. METHODOLOGY The study included 591 patients who underwent curative resection for node-positive gastric cancer. Clinicopathological prognostic variables were evaluated as predictors of long-term survival by univariate and multivariate analyses. RESULTS The 5-year survival rate was influenced by tumor size, tumor location, depth on invasion, level of lymph node metastasis, Borrmann classification, histological type, liver metastasis, peritoneal dissemination and disease stage. Of these, independent prognostic factors were depth on invasion and lymph node metastasis. Tumor size is an influence but not independent factor for the prediction of long-term survival in patients with node-positive gastric cancer. CONCLUSIONS In patients with node-positive gastric cancer, two independent prognostic factors were depth on invasion and the status of lymph node metastasis.
- Subjects :
- Oncology
Adult
Male
Prognostic variable
medicine.medical_specialty
Multivariate statistics
Multivariate analysis
Time Factors
Disease
Kaplan-Meier Estimate
Metastasis
Gastrectomy
Risk Factors
Stomach Neoplasms
Internal medicine
medicine
Odds Ratio
Humans
Neoplasm Invasiveness
Stage (cooking)
Survival rate
Aged
Proportional Hazards Models
Retrospective Studies
Chi-Square Distribution
Hepatology
business.industry
Carcinoma
Gastroenterology
Cancer
General Medicine
Middle Aged
medicine.disease
Tumor Burden
Survival Rate
Treatment Outcome
Lymphatic Metastasis
Multivariate Analysis
Female
business
Subjects
Details
- ISSN :
- 01726390
- Volume :
- 59
- Issue :
- 114
- Database :
- OpenAIRE
- Journal :
- Hepato-gastroenterology
- Accession number :
- edsair.doi.dedup.....c2b30023de7f390a7d99db0939fd6823