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Histological Grading of Transitional Cell Tumours of the Bladder Value of Histological Grading (WHO) in Prognosis
- Source :
- European Urology. 5:311-318
- Publication Year :
- 1979
- Publisher :
- Elsevier BV, 1979.
-
Abstract
- Mortality among 139 patients with transitional cell tumour of the bladder was studied. Tumours were reevaluated according to the grading system recommended by WHO. The absolute 5-year survival of histologically benign papilloma cases was 68%, of grade I carcinoma cases 64%, of grade II carcinoma cases 42% and of grade III carcinoma patients 34%. Clinical staging (UICC), however, would have been more effective than histological grading (WHO) for prognostic purposes. 3 of the 14 patients with histologically benign papilloma in this study developed grade I carcinoma during follow-up periods of between 4.5 and 24 years. Following radical treatment all recurrences were papillomas. The study suggests that histological grading should be used to complement clinical staging in prognosis and that with half-yearly check-ups and elimination of any tumours thus detected, patients with papilloma rarely develop carcinomas of higher grade than grade I.
- Subjects :
- Male
Radical treatment
Carcinoma, Transitional Cell
medicine.medical_specialty
business.industry
Urology
Urinary Bladder
Benign papilloma
Middle Aged
Prognosis
World Health Organization
medicine.disease
Carcinoma, Papillary
Urinary Bladder Neoplasms
Transitional Cell
Carcinoma
Humans
Medicine
Papilloma
Female
Radiology
business
Grading (education)
Aged
Follow-Up Studies
Subjects
Details
- ISSN :
- 18737560 and 03022838
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- European Urology
- Accession number :
- edsair.doi.dedup.....c24f5164611981a8d22fdcb19def1771