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Frailty measurement in research and clinical practice: A review
- Source :
- Dent, E, Kowal, P & Hoogendijk, E O 2016, ' Frailty measurement in research and clinical practice: A review ', European Journal of Internal Medicine, vol. 31, pp. 3-10 . https://doi.org/10.1016/j.ejim.2016.03.007, European Journal of Internal Medicine, 31, 3-10. Elsevier
- Publication Year :
- 2016
-
Abstract
- One of the leading causes of morbidity and premature mortality in older people is frailty. Frailty occurs when multiple physiological systems decline, to the extent that an individual's cellular repair mechanisms cannot maintain system homeostasis. This review gives an overview of the definitions and measurement of frailty in research and clinical practice, including: Fried's frailty phenotype; Rockwood and Mitnitski's Frailty Index (FI); the Study of Osteoporotic Fractures (SOF) Index; Edmonton Frailty Scale (EFS); the Fatigue, Resistance, Ambulation, Illness and Loss of weight (FRAIL) Index; Clinical Frailty Scale (CFS); the Multidimensional Prognostic Index (MPI); Tilburg Frailty Indicator (TFI); PRISMA-7; Groningen Frailty Indicator (GFI), Sherbrooke Postal Questionnaire (SPQ); the Gérontopôle Frailty Screening Tool (GFST) and the Kihon Checklist (KCL), among others. We summarise the main strengths and limitations of existing frailty measurements, and examine how well these measurements operationalise frailty according to Clegg's guidelines for frailty classification - that is: their accuracy in identifying frailty; their basis on biological causative theory; and their ability to reliably predict patient outcomes and response to potential therapies.
- Subjects :
- Aged, 80 and over
Gerontology
medicine.medical_specialty
business.industry
Frail Elderly
Frailty Index
Kihon checklist
Frailty phenotype
Clinical Practice
03 medical and health sciences
Postal questionnaire
0302 clinical medicine
Activities of Daily Living
Internal Medicine
Physical therapy
Humans
Medicine
Screening tool
030212 general & internal medicine
business
Older people
Groningen Frailty Indicator
Geriatric Assessment
030217 neurology & neurosurgery
Aged
Subjects
Details
- Language :
- English
- ISSN :
- 09536205
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- European Journal of Internal Medicine
- Accession number :
- edsair.doi.dedup.....c24d038c11dc0c4d352f89cc441bff9c