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A facile approach for the delivery of inorganic nanoparticles into the brain by passing through the blood-brain barrier (BBB)

Authors :
Yeong Shin Yim
Dong Goo Kim
Gun Tae Kim
Jinwoo Cheon
Tae Hyun Shin
Jin Sil Choi
Chul Hoon Kim
Source :
Chemical communications (Cambridge, England). 48(1)
Publication Year :
2011

Abstract

This study provides an easy and simple method to obtain inorganic nanoparticles that can penetrate the blood–brain barrier, the heavily guarded system in the brain, via cross-linked serum albumin surface coatings. Their intact BBB permeability was confirmed in both in vitro and in vivo tests.

Details

ISSN :
1364548X
Volume :
48
Issue :
1
Database :
OpenAIRE
Journal :
Chemical communications (Cambridge, England)
Accession number :
edsair.doi.dedup.....c248cb57183a241ef27693463ef00b2e