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A facile approach for the delivery of inorganic nanoparticles into the brain by passing through the blood-brain barrier (BBB)
- Source :
- Chemical communications (Cambridge, England). 48(1)
- Publication Year :
- 2011
-
Abstract
- This study provides an easy and simple method to obtain inorganic nanoparticles that can penetrate the blood–brain barrier, the heavily guarded system in the brain, via cross-linked serum albumin surface coatings. Their intact BBB permeability was confirmed in both in vitro and in vivo tests.
- Subjects :
- Serum albumin
Nanotechnology
Blood–brain barrier
In vivo tests
Ferric Compounds
Catalysis
Permeability
Mice
Materials Chemistry
medicine
Animals
Serum Albumin
Neurons
biology
Chemistry
fungi
Metals and Alloys
food and beverages
Endothelial Cells
Biological Transport
General Chemistry
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
medicine.anatomical_structure
Permeability (electromagnetism)
Blood-Brain Barrier
Astrocytes
Ceramics and Composites
biology.protein
Biophysics
Nanoparticles
Bbb permeability
Inorganic nanoparticles
Subjects
Details
- ISSN :
- 1364548X
- Volume :
- 48
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Chemical communications (Cambridge, England)
- Accession number :
- edsair.doi.dedup.....c248cb57183a241ef27693463ef00b2e