2080 Relationship of structural and functional cardiac abnormalities to respiratory status in Duchenne Muscular Dystrophy

Methods Retrospective cross-sectional study of 40 DMD subjects evaluated from 2004–2006. Each patient underwent standard pulmonary function testing and CMR for clinical indications (mean = 9 months between studies). Collected data included FVC% predicted (FVC%, a marker of ventilatory capacity) and FEV1%; Ejection fraction (LVEF, RVEF), end-diastolic volume (LVEDV, RVEDV), and enddiastolic mass (LVEDM, RVEDM). Spearman rank correlations were performed between pulmonary and cardiac parameters.