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Molecular Detection of Microorganisms Associated with Small Mammals and Their Ectoparasites in Mali
- Source :
- American Journal of Tropical Medicine and Hygiene, American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2020, 103 (6), pp.2542-2551. ⟨10.4269/ajtmh.19-0727⟩, Am J Trop Med Hyg, American Journal of Tropical Medicine and Hygiene, 2020, 103 (6), pp.2542-2551. ⟨10.4269/ajtmh.19-0727⟩
- Publication Year :
- 2020
- Publisher :
- HAL CCSD, 2020.
-
Abstract
- Small mammals are the natural reservoirs for many zoonotic pathogens. Using molecular tools, we assessed the prevalence of bacteria and protozoans in small mammals and their ectoparasites in Faladje, Bougouni, and Bamoko, Mali. A total of 130 small mammals belonging to 10 different species were captured, of which 74 (56.9%) were infested by ectoparasites, including Laelaps echidnina, Xenopsylla cheopis, Amblyomma variegatum, Rhipicephalus sanguineus sensu lato, and Haemaphysalis spp. nymphs. DNA of Bartonella was found in 14/75 (18.7%), 6/48 (12.5%), and 3/7 (42.8%) small mammals from Faladje, Bougouni, and Bamako, respectively. In Faladje, Bartonella DNA was detected in 31/68 (45.6%) of L. echidnina and 14/22 (63.6%) of X. cheopis. In Bougouni, it was found in 2/26 (7.7%) of L. echidnina and 10/42 (23.8%) of X. cheopis. The sequences of Bartonella obtained from small mammals were close to those of Bartonella mastomydis, Bartonella elizabethae, and uncultured Bartonella spp. In Faladje, Coxiella burnetii DNA was detected in 64.4% (29/45) of Haemaphysalis spp. ticks, 4.5% (2/44) of Mastomys erythroleucus, 12.5% (1/8) of Praomys daltoni, and 1.5% (1/68) of L. echidnina. We found DNA of Wolbachia in X. cheopis from Faladje and DNA of Rickettsia africae and Ehrlichia ruminantium in Am. variegatum from Bougouni. The results of our study show that several small mammal species harbor and may serve as potential reservoirs of Bartonella spp., likely to play a major role in the maintenance, circulation, and potential transmission of bacteria in Mali. The pathogenicity of these bacteria for humans or animals remains to be demonstrated.
- Subjects :
- Bartonella
Disease reservoir
Rhipicephalus sanguineus
030231 tropical medicine
Rodentia
Ectoparasitic Infestations
Ehrlichia ruminantium
Mali
Microbiology
Rodent Diseases
03 medical and health sciences
0302 clinical medicine
Ticks
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Virology
Zoonoses
Animals
[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology
Phylogeny
ComputingMilieux_MISCELLANEOUS
Disease Reservoirs
Mites
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases
biology
Bacteria
Articles
biology.organism_classification
Rickettsia africae
Haemaphysalis
[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology
Bartonella elizabethae
Infectious Diseases
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
Siphonaptera
Parasitology
Amblyomma variegatum
Subjects
Details
- Language :
- English
- ISSN :
- 00029637
- Database :
- OpenAIRE
- Journal :
- American Journal of Tropical Medicine and Hygiene, American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2020, 103 (6), pp.2542-2551. ⟨10.4269/ajtmh.19-0727⟩, Am J Trop Med Hyg, American Journal of Tropical Medicine and Hygiene, 2020, 103 (6), pp.2542-2551. ⟨10.4269/ajtmh.19-0727⟩
- Accession number :
- edsair.doi.dedup.....c22d93e667ea3b1876317cd5bd214466