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The Association between Kidney Function, Coronary Artery Disease, and Clinical Outcome in Patients Undergoing Coronary Angiography
- Source :
- Journal of Korean Medical Science
- Publication Year :
- 2009
- Publisher :
- The Korean Academy of Medical Sciences, 2009.
-
Abstract
- To characterize the association between chronic kidney disease (CKD), mortality, severity of coronary artery disease (CAD), treatment modality of CAD, and type of coronary stents among patients undergoing coronary angiography (CAG), we retrospectively reviewed the electronic medical records of the patients who underwent CAG at Seoul National University Bundang Hospital in Korea between May 2003 and January 2006. CKD was staged using an estimated glomerular filtration rate (eGFR) from the creatinine value prior to CAG. There were 3,637 patients included. The presence of CAD was 48% in CKD stage 1, 61% in stage 2, 73% in stage 3, 87% in stage 4, and 81% in stage 5. Survival rate gradually diminished for patients with decreasing renal function. No significant differences in all-cause and cardiac mortality were observed by medical treatment, PCI or CABG, in CKD patients with an eGFR less than 60 mL/min/1.73 m(2). CKD patients with drug-eluting stents showed significantly lower all-cause mortality (5.4% vs. 13.3%) and incidence of myocardial infarction (1.7% vs. 10%) than those with bare metal stents. In conclusion, an eGFR is a strong independent prognostic marker among patients undergoing CAG and the severity of CAD increases progressively with worsening renal function.
- Subjects :
- Drug-eluting Stents
Male
medicine.medical_specialty
Time Factors
Renal function
Coronary Artery Disease
urologic and male genital diseases
Coronary Angiography
Kidney
Kidney Function Tests
Coronary artery disease
chemistry.chemical_compound
Internal medicine
medicine
Humans
Myocardial infarction
cardiovascular diseases
Mortality
Survival rate
Aged
Creatinine
business.industry
Incidence (epidemiology)
General Medicine
Middle Aged
medicine.disease
Treatment Outcome
chemistry
Conventional PCI
Hypertension
Cardiology
Kidney Failure, Chronic
Original Article
Female
Kidney Diseases
Stents
business
Kidney disease
Glomerular Filtration Rate
Subjects
Details
- Language :
- English
- ISSN :
- 15986357 and 10118934
- Volume :
- 24
- Issue :
- Suppl 1
- Database :
- OpenAIRE
- Journal :
- Journal of Korean Medical Science
- Accession number :
- edsair.doi.dedup.....c208c6cdab342269a7d2b13d67083449