Back to Search Start Over

Radical parametrectomy after 'cut-through' hysterectomy in low-risk early-stage cervical cancer: Time to consider this procedure obsolete

Authors :
Mireia Gonzalez-Comadran
Rene Pareja
Daniel Sanabria
Lina Echeverri
David Isla
Pedro T. Ramirez
Mark F. Munsell
Gabriel J. Rendón
Michael Frumovitz
Source :
Gynecologic oncology. 149(3)
Publication Year :
2017

Abstract

Objective The goal of this study is to identify predictive factors in patients with a diagnosis of early-stage cervical cancer after simple hysterectomy in order to avoid a radical parametrectomy. Methods A retrospective review was performed of all patients who underwent radical parametrectomy and bilateral pelvic lymphadenectomy at MD Anderson Cancer Center and at the Instituto de Cancerologia Las Americas in Medellin, Colombia from December 1999 to September 2017. We sought to determine the outcomes in patients diagnosed with low-risk factors (squamous, adenocarcinoma or adenosquamous lesions Results A total of 30 patients were included in the study. The median age was 40.4years (range; 26–60) and median body mass index (BMI) was 26.4kg/m 2 (range; 17.7–40.0). A total 22 patients had tumors Conclusion Radical parametrectomy may be avoided in patients with low-risk early-stage cervical cancer detected after a simple hysterectomy. Rates of residual disease (parametrial or vaginal) and the need for adjuvant treatments or recurrences are very low.

Details

ISSN :
10956859
Volume :
149
Issue :
3
Database :
OpenAIRE
Journal :
Gynecologic oncology
Accession number :
edsair.doi.dedup.....c19e2e28cef45aac744f1e952c06a9de