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Antioxidant and anti-inflammatory activities of Phlomis pungens and Coridothymus capitatus
- Source :
- Marmara Pharmaceutical Journal. 22:80-85
- Publication Year :
- 2018
- Publisher :
- Marmara Pharmaceutical Journal, 2018.
-
Abstract
- The purpose of this study was to comparatively reveal for the first time the antioxidant, anti-inflammatory effects of Phlomis pungens and Coridothymus capitatus methanol extracts obtained by using maceration extraction method. According to the results of anti-inflammatory activity, P. pungens methanolic extract demonstrated a more prominent and intensive antiinflammatory effect with 24.7% of inhibitive capacity in the altered edema size after the first hour of carrageenan injection compared to C. capitatus methanolic extract. P. pungens methanolic extract inhibitory effect increased during three hours and reached maximum by 41.9%. According to the results obtained from antioxidant activity experiments, methanol extract of C. capitatus exhibited stronger free radical scavenging (DPPH), cupric reducing (CUPRAC), ferric reducing/antioxidant power (FRAP) and ABTS radical cation scavenging activity than P. pungens extract. In additon, C. capitatus extract had higher ABTS radical cation scavenging and ferric reducing/antioxidant power activity than ascorbic acid, BHT and BHA, respectively. Therefore, this extract can be used in both medicine and food industry as a natural antioxidant source.
- Subjects :
- antioxidant
Antioxidant
medicine.drug_class
medicine.medical_treatment
Pharmacology toxicology
02 engineering and technology
Biology
P. pungens
CHEMICAL-COMPOSITION
010402 general chemistry
01 natural sciences
Anti-inflammatory
C. capitatus
medicine
PLANTS
Pharmacology (medical)
Coridothymus capitatus
General Pharmacology, Toxicology and Pharmaceutics
anti-inflammatory
Traditional medicine
EXTRACT
WILD
021001 nanoscience & nanotechnology
biology.organism_classification
0104 chemical sciences
Phlomis
ESSENTIAL OILS
0210 nano-technology
IN-VITRO ANTIOXIDANT
Subjects
Details
- ISSN :
- 13090801
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Marmara Pharmaceutical Journal
- Accession number :
- edsair.doi.dedup.....c176c5b0eebdebb73fd36f8ccfb58606