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Healthy adolescent performance on the MATRICS Consensus Cognitive Battery (MCCB): Developmental data from two samples of volunteers
- Source :
- Schizophrenia Research. 172:106-113
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- The MATRICS Consensus Cognitive Battery (MCCB) fills a significant need for a standardized battery of cognitive tests to use in clinical trials for schizophrenia in adults aged 20-59. A need remains, however, to develop norms for younger individuals, who also show elevated risks for schizophrenia. Toward this end, we assessed performance in healthy adolescents. Baseline MCCB, reading and IQ data were obtained from healthy controls (ages 12-19) participating in two concurrent NIMH-funded studies: North American Prodromal Longitudinal Study phase 2 (NAPLS-2; n=126) and Boston Center for Intervention Development and Applied Research (CIDAR; n=13). All MCCB tests were administered except the Managing Emotions subtest from the Mayer-Salovey-Caruso Emotional Intelligence Test. Data were collected from 8 sites across North America. MCCB scores were presented in four 2-year age cohorts as T-scores for each test and cognitive domain, and analyzed for effects of age and sex. Due to IQ differences between age-grouped subsamples, IQ served as a covariate in analyses. Overall and sex-based raw scores for individual MCCB tests are presented for each age-based cohort. Adolescents generally showed improvement with age in most MCCB cognitive domains, with the clearest linear trends in Speed of Processing, Attention/Vigilance, and Working Memory. These control data show that healthy adolescence is a dynamic period for cognitive development that is marked by substantial improvement in MCCB performance through the 12-19 age range. They also provide healthy comparison raw scores to facilitate clinical evaluations of adolescents, including those at risk for developing psychiatric disorders such as schizophrenia-related conditions.
- Subjects :
- Male
medicine.medical_specialty
Longitudinal study
Adolescent
Psychology, Adolescent
Article
Cohort Studies
03 medical and health sciences
Cognition
0302 clinical medicine
Reference Values
Cognitive development
medicine
Humans
Raw score
Psychological testing
Longitudinal Studies
Child
Psychiatry
Biological Psychiatry
Psychological Tests
Emotional intelligence
Age Factors
030227 psychiatry
Cognitive test
Psychiatry and Mental health
Psychotic Disorders
Schizophrenia
Female
Schizophrenic Psychology
Psychology
030217 neurology & neurosurgery
Clinical psychology
Cohort study
Subjects
Details
- ISSN :
- 09209964
- Volume :
- 172
- Database :
- OpenAIRE
- Journal :
- Schizophrenia Research
- Accession number :
- edsair.doi.dedup.....c1314ae8d1ddde40727af3dc7759cf03
- Full Text :
- https://doi.org/10.1016/j.schres.2016.02.003