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The influence of different cellulose ethers on both the handling and mechanical properties of calcium phosphate cements for bone substitution
- Source :
- Acta Biomaterialia, Acta Biomaterialia, Elsevier, 2013, 9 (3), pp.5740. ⟨10.1016/j.actbio.2012.11.020⟩
- Publication Year :
- 2012
-
Abstract
- International audience; The influence of cellulose ether additives (CEAs) on the performance of final calcium phosphate cement (CPC) products is thoroughly investigated. Four CEAs were added into the liquid phase of apatitic CPCs based on the hydrolysis of α-tricalcium phosphate, to investigate the influence of both molecular weight and degree of substitution on the CPCs' properties, including handling (e.g. injectability, cohesion, washout resistance and setting time), microstructure (e.g. porosity and micromorphology) and mechanical properties (e.g. fracture toughness and compressive strength). The results showed that even a small amount of CEAs modified most of these CPCs' features, depending on the structural parameters of the CEAs. The CEAs dramatically improved the injectability, cohesion and washout resistance of the pastes, prolonged the final setting time and increased the porosity of CPCs. Moreover, the CEAs had an evident toughening effect on CPCs, and this effect become more significant with increasing molecular weight and mass fraction of CEAs, inducing a significant tolerance to damage. Overall, the molecular weight of CEAs played a major role compared to their degree of substitution in CPCs' performances.
- Subjects :
- Calcium Phosphates
Materials science
Time Factors
Biomedical Engineering
chemistry.chemical_element
02 engineering and technology
Calcium
Biochemistry
Bone and Bones
Injections
Biomaterials
03 medical and health sciences
chemistry.chemical_compound
Hydrolysis
Fracture toughness
HPMC
Apatitic biocement
Cellulose
Composite material
Polysaccharide
Porosity
neoplasms
Molecular Biology
030304 developmental biology
Mechanical Phenomena
0303 health sciences
Bone Cements
General Medicine
021001 nanoscience & nanotechnology
Phosphate
Microstructure
digestive system diseases
Compressive strength
chemistry
[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]
Microscopy, Electron, Scanning
Handling properties
Stress, Mechanical
0210 nano-technology
Biotechnology
Ethers
Subjects
Details
- ISSN :
- 18787568 and 17427061
- Volume :
- 9
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Acta biomaterialia
- Accession number :
- edsair.doi.dedup.....c12eee2b274510f3a2029101f75146cf