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Etanercept treatment-related c-ANCA-associated large vessel vasculitis
- Source :
- Clinical Rheumatology. 35:271-273
- Publication Year :
- 2015
- Publisher :
- Springer Science and Business Media LLC, 2015.
-
Abstract
- Anti-tumor necrosis factor (TNF) agents have become central players in the management of autoimmune and rheumatic disease. With the wide use of anti-TNF agents today, we have become aware of rare autoimmune complications as systemic lupus erythematosus and psoriasis, yet rarely has large vessels vasculitis been described. We herein describe a case of cytoplasmic anti-neutrophil cytoplasmic antibody (c-ANCA) (with myeloperoxidase (MPO) antibodies)-associated large vessel vasculitis (aortitis) that developed during anti-TNF treatment for ankylosing spondylitis. Awareness of this rare, but serious, adverse event of these commonly used agents in rheumatic diseases is of importance.
- Subjects :
- Radiography, Abdominal
medicine.medical_specialty
C-ANCA
030204 cardiovascular system & hematology
Antibodies, Antineutrophil Cytoplasmic
Etanercept
03 medical and health sciences
0302 clinical medicine
Rheumatology
Prednisone
Rheumatic Diseases
Internal medicine
Large vessel vasculitis
medicine
Humans
Spondylitis, Ankylosing
Aortitis
Aged
030203 arthritis & rheumatology
Ankylosing spondylitis
Tumor Necrosis Factor-alpha
business.industry
General Medicine
medicine.disease
Immunology
Female
Rituximab
Tomography, X-Ray Computed
Vasculitis
business
medicine.drug
Subjects
Details
- ISSN :
- 14349949 and 07703198
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Clinical Rheumatology
- Accession number :
- edsair.doi.dedup.....c12e859bb0122116ca16df56bb04ee23
- Full Text :
- https://doi.org/10.1007/s10067-015-3134-4