Hypocholesterolemic Properties of Protein Isolate from Cowpeas (Vigna Unguiculata) Sprout in Normal and Diabetic Rats

This research was aimed to determine the potency of hypocholestrolemic properties of protein isolate from cowpeas sprout through in vivo bioassay by using Sprague Dawley male rats. The treatments of the research were rat conditions (normal and diabeic rats) and feed treatments (standard and protein isolate feed). Blood triglyceride, cholesterol total, High Density Lipoprotein (HDL), and Low Density Lipoprotein (LDL), of rats were analysed on 3 th , 6 th , 9 th , 12 th , 15 th days for the treatment and before treatment as control. The result of this research showed that the blood triglyceride, cholesterol total, LDL decreased and the blood HDL increased in diabetics rats with protein isolate treatment. The potency of hypocholestrolemic activity were shown by the ratio of cholesterol total/HDL and LDL/HDL. The ratio of the rats were normal, exception diabetic rats with standart feed.