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Beneficial role of Boehmeria nivea in health and phytochemical constituents
- Source :
- Journal of food biochemistryREFERENCES.
- Publication Year :
- 2022
-
Abstract
- The leaf and stem extracts of Boehmeria nivea (BN) collected from three different regions in Korea were screened for their antioxidant, neuroprotective, estrogenic, insulin secretion, and α-glucosidase inhibitory activity. We also examined whether BN extracts regulate cancer cell growth, inflammatory-related gene expression, and lipid accumulation in cellular system. Leaf extracts possessed greater antioxidant, anti-proliferative in cancer cells, neuroprotective, estrogenic activity, and inhibitory effect on pro-inflammatory gene expression than stem extracts. Leaf and stem extracts inhibited lipid accumulation in three T3-L1 adipocytes but did not affect glucose-stimulated insulin secretion in INS-1 cells. We isolated and identified the phytochemical constituents in the n-butanol and ethyl acetate fractions of BN leaves by combining silica gel column chromatography with mass spectrometry and
- Subjects :
- Pharmacology
Biophysics
Cell Biology
Food Science
Subjects
Details
- ISSN :
- 17454514
- Database :
- OpenAIRE
- Journal :
- Journal of food biochemistryREFERENCES
- Accession number :
- edsair.doi.dedup.....c0eb4e2e3ec006b821f05cf024930979