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The Value of Ultrasound-Guided Fine-Needle Aspiration Cytology Combined with Puncture Feeling in the Diagnosis of Thyroid Nodules
- Source :
- Acta Cytologica. 65:368-376
- Publication Year :
- 2021
- Publisher :
- S. Karger AG, 2021.
-
Abstract
- Introduction: There are few studies on the role of puncture feeling in thyroid nodules during ultrasound-guided fine-needle aspiration cytology (US-FNAC), although it is expected to become a new predictive technique. We aimed to analyze the importance of puncture feeling in combination with US-FNAC and investigate whether it can be used as an indicator to predict the nature of thyroid nodules. Materials and Methods: From January 1, 2018, to October 31, 2020, a total of 623 thyroid nodules were included. Puncture feeling was classified as “soft,” “hard,” or “hard with grittiness.” The correlation between puncture feeling and postoperative pathology and the diagnostic value of FNAC combined with puncture feeling were analyzed, and the influence of thyroid nodule size on puncture feeling, FNAC, and FNAC combined with puncture feeling was studied. We further explored the correlation between puncture feeling and histopathology in Bethesda III and IV thyroid nodules. Results: There was a significant correlation between puncture feeling and postoperative pathology (p < 0.001). The sensitivity, negative predictive value, and total coincidence rate of US-FNAC combined with puncture feeling for the diagnosis of thyroid nodules were higher than those of US-FNAC alone (96.1, 83.6, and 94.7% vs. 89.0, 65.5, and 89.7%, respectively). Thyroid nodule size was the influencing factor for puncture feeling, FNAC, and FNAC combined with puncture feeling (p < 0.05 for all). The area under the curve for puncture feeling, FNAC, and FNAC combined with puncture feeling for thyroid nodules of size ≤1 cm was greater than for modules of size >1 cm. Puncture feeling was of great value in diagnosing Bethesda III thyroid nodules (p < 0.001), and all Bethesda IV thyroid nodules had puncture feeling of soft. Conclusion: Puncture feeling is of great value during US-FNAC. “Hard” and “hard with grittiness” were indicators for malignancy, while “soft” indicated that the thyroid nodule was likely to be benign. The diagnostic value of US-FNAC combined with puncture feeling for thyroid nodules is higher than US-FNAC alone, especially when nodule size is ≤1 cm. Puncture feeling is of great value in predicting the nature of Bethesda III thyroid nodules.
- Subjects :
- Image-Guided Biopsy
Thyroid nodules
medicine.medical_specialty
Histology
Cytodiagnosis
media_common.quotation_subject
Biopsy, Fine-Needle
Cytological Techniques
Thyroid Gland
Punctures
Malignancy
Pathology and Forensic Medicine
Predictive Value of Tests
Fine needle aspiration cytology
medicine
Humans
Thyroid Neoplasms
Thyroid Nodule
Ultrasonography
media_common
business.industry
Thyroid
Nodule (medicine)
General Medicine
Middle Aged
medicine.disease
Ultrasound guided
Aspiration cytology
body regions
medicine.anatomical_structure
Feeling
Radiology
medicine.symptom
business
Subjects
Details
- ISSN :
- 19382650 and 00015547
- Volume :
- 65
- Database :
- OpenAIRE
- Journal :
- Acta Cytologica
- Accession number :
- edsair.doi.dedup.....c0ce846112add0012684f94e6f790c67