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Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040
- Source :
- Sonnenschein, E, Stierhof, M, Goralczyk, S, Vabre, F M, Pellissier, L, Hanssen, K Ø, de la Cruz, M, Díaz, C, de Witte, P, Copmans, D, Andersen, J H, Hansen, E, Kristoffersen, V, Tormo, J R, Ebel, R, Milne, B F, Deng, H, Gram, L, Jaspars, M & Tabudravu, J N 2017, ' Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040 ', Tetrahedron, vol. 73, no. 18, pp. 2633-2637 . https://doi.org/10.1016/j.tet.2017.03.051
- Publication Year :
- 2017
- Publisher :
- Elsevier, 2017.
-
Abstract
- A new siderophore containing a 4,5-dihydroimidazole moiety was isolated from Pseudoalteromonas piscicida S2040 together with myxochelins A and B, alteramide A and its cycloaddition product, and bromo- and dibromoalterochromides. The structure of pseudochelin A was established by spectroscopic techniques including 2D NMR and MS/MS fragmentation data. In bioassays selected fractions of the crude extract of S2040 inhibited the opportunistic pathogen Pseudomonas aeruginosa. Pseudochelin A displayed siderophore activity in the chrome azurol S assay at concentrations higher than 50 mu M, and showed weak activity against the fungus Aspergillus fumigatus, but did not display antibacterial, anti-inflammatory or anticonvulsant activity. (C) 2017 Elsevier Ltd. All rights reserved.
- Subjects :
- 0301 basic medicine
Mycobacterium-tuberculosis
030106 microbiology
F100
Microorganisms
Siderocalin
Library science
010402 general chemistry
01 natural sciences
Biochemistry
03 medical and health sciences
LCMS
Siderophore
Drug Discovery
Vibrio-cholerae
Pseudomonas-aeruginosa
Pyochelin
Microbial iron transport
biology
Chemistry
Organic Chemistry
biology.organism_classification
NMR
Coordination chemistry
0104 chemical sciences
3. Good health
Recognition
Pseudoalteromonas
Acquisition
Pseudoalteromonas piscicida
Pseudochelin A
Subjects
Details
- Language :
- English
- ISSN :
- 00404020
- Database :
- OpenAIRE
- Journal :
- Sonnenschein, E, Stierhof, M, Goralczyk, S, Vabre, F M, Pellissier, L, Hanssen, K Ø, de la Cruz, M, Díaz, C, de Witte, P, Copmans, D, Andersen, J H, Hansen, E, Kristoffersen, V, Tormo, J R, Ebel, R, Milne, B F, Deng, H, Gram, L, Jaspars, M & Tabudravu, J N 2017, ' Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040 ', Tetrahedron, vol. 73, no. 18, pp. 2633-2637 . https://doi.org/10.1016/j.tet.2017.03.051
- Accession number :
- edsair.doi.dedup.....c0cae24211479d17427992c872c3cc44
- Full Text :
- https://doi.org/10.1016/j.tet.2017.03.051