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Proton beam therapy for a giant hepatic hemangioma: A case report and literature review
- Source :
- Clinical and Translational Radiation Oncology, Clinical and Translational Radiation Oncology, Vol 27, Iss, Pp 152-156 (2021)
- Publication Year :
- 2021
- Publisher :
- Elsevier, 2021.
-
Abstract
- Highlights • Proton beam therapy is likely to be safe for liver hemangiomas because, in our experience. • Proton beam therapy achieves good local control for liver hemangiomas without causing severe hepatic damage. • Proton beam therapy expected to minimize the risk of late adverse events.<br />Background Hepatic hemangiomas are benign tumors with a favorable prognosis, but giant hepatic hemangiomas can cause abdominal symptoms and are indicated for treatment. Most cases are treated with surgery, but radiotherapy has also been used. However, to date, there have been no reports of proton beam therapy for a hepatic hemangioma. Case presentation A 46-year-old woman had a tumor of 80 × 80 mm in the left medial lobe of the liver, which was diagnosed as a giant hemangioma based on the contrast pattern. Therapy was required for a giant hepatic hemangioma with symptoms, but the patient refused blood transfusion due to religious reasons, which made surgical resection difficult. Therefore, she was referred to our hospital for proton beam therapy. At her first visit, liver function was Child-Pugh A (5 points) and there was no elevation of tumor markers. Proton beam therapy of 28.6 Gy (RBE) given in 13 fractions was performed without interruption. The only observed acute radiation toxicity was Grade 1 dermatitis. One year after proton beam therapy, the hemangioma had significantly decreased, and a complete response has been maintained for 15 years based on ultrasound and MRI. Conclusion This case is the first reported use of proton beam therapy for a hepatic hemangioma. The outcome suggests that this treatment may be effective for a giant liver hemangioma.
- Subjects :
- Hepatic Hemangioma
medicine.medical_specialty
Blood transfusion
Proton beam therapy
medicine.medical_treatment
R895-920
Case Report
030218 nuclear medicine & medical imaging
Hemangioma
Medical physics. Medical radiology. Nuclear medicine
03 medical and health sciences
0302 clinical medicine
medicine
Radiology, Nuclear Medicine and imaging
RC254-282
Radiotherapy
business.industry
Ultrasound
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Giant Hemangioma
medicine.disease
eye diseases
Radiation therapy
Liver
Oncology
030220 oncology & carcinogenesis
Liver Hemangioma
Radiology
Liver function
sense organs
Secondary cancer
business
Subjects
Details
- Language :
- English
- ISSN :
- 24056308
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Clinical and Translational Radiation Oncology
- Accession number :
- edsair.doi.dedup.....c09219bdc3446e2d8bc6b4cfe0584bb3