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Consensus document on controversial issues in the diagnosis and treatment of prosthetic joint infections
- Publication Year :
- 2010
-
Abstract
- Summary Background Joint replacement surgery has been on the increase in recent decades and prosthesis infection remains the most critical complication. Many aspects of the primary prevention and clinical management of such prosthesis infections still need to be clarified. Controversial issues The aim of this GISIG (Gruppo Italiano di Studio sulle Infezioni Gravi) working group – a panel of multidisciplinary experts – was to define recommendations for the following controversial issues: (1) Is a conservative surgical approach for the management of prosthetic joint infections effective? (2) Is the one-stage or the two-stage revision for the management of prosthetic joint infections more effective? (3) What is the most effective treatment for the management of prosthetic joint infections due to methicillin-resistant staphylococci? Results are presented and discussed in detail. Methods A systematic literature search using the MEDLINE database for the period 1988 to 2008 of randomized controlled trials and/or non-randomized studies was performed. A matrix was created to extract evidence from original studies using the CONSORT method to evaluate randomized clinical trials and the Newcastle–Ottawa Quality Assessment Scale for case–control studies, longitudinal cohorts, and retrospective studies. The GRADE method for grading quality of evidence and strength of recommendation was applied.
- Subjects :
- Microbiology (medical)
Methicillin-Resistant Staphylococcus aureus
medicine.medical_specialty
one-stage approach
Prosthesis-Related Infections
methicillin-resistant staphylococci
Joint replacement
Prosthetic joint
medicine.medical_treatment
Staphylococcus
prosthetic joint infections
Prosthesis
law.invention
Randomized controlled trial
Staphylococcu
Multidisciplinary approach
law
medicine
Humans
Hip Prosthesi
prosthetic joint infection
Prosthesis-Related Infection
Intensive care medicine
Randomized Controlled Trials as Topic
Clinical Trials as Topic
conservative surgical approach
Evidence-Based Medicine
business.industry
Methicillin-Resistant Staphylococcus aureu
two-stage approach
Retrospective cohort study
Knee Prosthesi
General Medicine
Evidence-based medicine
Staphylococcal Infections
Surgery
Hip Prosthesis
Knee Prosthesis
Treatment Outcome
Infectious Diseases
CONSENSUS
Medline database
business
Human
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....c08b8072c6ef14ae4ff83c53a059e3cb