Back to Search
Start Over
T(H)1 cells control themselves by producing interleukin-10
T(H)1 cells control themselves by producing interleukin-10
- Source :
- Nature Reviews Immunology, Nature Reviews Immunology, Nature Publishing Group, 2007, 7 (6), pp.425-8. ⟨10.1038/nri2097⟩, Nature Reviews Immunology, 2007, 7 (6), pp.425-8. ⟨10.1038/nri2097⟩
- Publication Year :
- 2007
- Publisher :
- HAL CCSD, 2007.
-
Abstract
- International audience; Inflammatory T helper 1 (T(H)1)-cell responses successfully eradicate pathogens, but often also cause immunopathology. To minimize this deleterious side-effect the anti-inflammatory cytokine interleukin-10 (IL-10) is produced. Although IL-10 was originally isolated from T(H)2 cells it is now known to be produced by many cell types. Here, we discuss the recent evidence that shows that T(H)1 cells are the main source of IL-10 that controls the immune response against Leishmania major and Toxoplasma gondii infection.
- Subjects :
- History
Cell type
MESH: Interleukin-10
medicine.medical_treatment
Leishmaniasis, Cutaneous
MESH: Models, Immunological
Education
Microbiology
03 medical and health sciences
0302 clinical medicine
Immune system
Immunopathology
parasitic diseases
medicine
Animals
Humans
Leishmania major
MESH: Animals
030304 developmental biology
0303 health sciences
MESH: Humans
biology
Models, Immunological
Toxoplasma gondii
Th1 Cells
biology.organism_classification
MESH: Leishmaniasis, Cutaneous
Interleukin-10
3. Good health
Computer Science Applications
Interleukin 10
Cytokine
T helper 1
MESH: Th1 Cells
Immunology
MESH: Toxoplasmosis
[SDV.IMM]Life Sciences [q-bio]/Immunology
Toxoplasmosis
030215 immunology
Subjects
Details
- Language :
- English
- ISSN :
- 14741741
- Database :
- OpenAIRE
- Journal :
- Nature Reviews Immunology, Nature Reviews Immunology, Nature Publishing Group, 2007, 7 (6), pp.425-8. ⟨10.1038/nri2097⟩, Nature Reviews Immunology, 2007, 7 (6), pp.425-8. ⟨10.1038/nri2097⟩
- Accession number :
- edsair.doi.dedup.....c089eb5bac0723395cba9d164e35cd22
- Full Text :
- https://doi.org/10.1038/nri2097⟩