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Genetic background of adrenocortical tumor development
- Source :
- World journal of surgery. 25(7)
- Publication Year :
- 2001
-
Abstract
- The increasing occurrence of incidentally discovered benign adrenocortical tumors has become a clinical dilemma because of the difficulties in differentiating them from their malignant counterpart. Adrenocortical tumors are associated with familial cancer syndromes such as the Beckwith-Wiedemann syndrome, the Li-Fraumeni syndrome, the Carney complex, multiple endocrine neoplasia type 1, congenital adrenal hyperplasia, and the McCune-Albright syndrome. Genetic events are known to take place on the chromosomal and gene level in sporadic adrenocortical tumors.
- Subjects :
- congenital, hereditary, and neonatal diseases and abnormalities
Pathology
medicine.medical_specialty
business.industry
Adrenal cortex
Adrenalectomy
medicine.medical_treatment
Adrenocortical Tumor
medicine.disease
Genetic determinism
Adrenal Cortex Neoplasms
medicine.anatomical_structure
Adrenal Cortex
Medicine
Humans
Surgery
Congenital adrenal hyperplasia
Familial Cancer
business
Multiple endocrine neoplasia
Carney complex
Subjects
Details
- ISSN :
- 03642313
- Volume :
- 25
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- World journal of surgery
- Accession number :
- edsair.doi.dedup.....c07c07d120253148666ba28514a37427