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Glutathione-Sensitive Silicon Nanowire Arrays for Gene Transfection

Authors :
Sixuan Zhang
Yuping Liu
Xuejin Huang
Hong Chen
Lin Yuan
Yingxian Zhao
Ya Sun
Jinghong Wang
Hongwei Wang
Source :
ACS Applied Materials & Interfaces. 11:46515-46524
Publication Year :
2019
Publisher :
American Chemical Society (ACS), 2019.

Abstract

Ingenious surface modification strategies and special topological morphologies endow the biomaterial interface with excellent ability to regulate the cell fate. In this work, a gene delivery platform based on glutathione-sensitive silicon nanowire arrays (SiNWAs) is developed, exhibiting good transfection efficiency of several cell types. Briefly, the surface of SiNWAs is grafted of PEI

Details

ISSN :
19448252 and 19448244
Volume :
11
Database :
OpenAIRE
Journal :
ACS Applied Materials & Interfaces
Accession number :
edsair.doi.dedup.....c07a3795d4b28c8c21210032b157ff0f
Full Text :
https://doi.org/10.1021/acsami.9b17006