Reduced infiltration of microglia/macrophages based on CCR2-deficiency considerably enhances glioma progression

Authors :: Felsenstein, Matthäus
Brandenburg, Susan
Turkowski, Kati
Vajkoczy, Peter
Source :: 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20150607-20150610; Karlsruhe; DOCDI.03.02 /20150602/
Publication Year :: 2015
Publisher :: German Medical Science GMS Publishing House; Düsseldorf, 2015.
Abstract: Objective: Glioblastoma multiforme belongs to malignant glial tumors, and is extremely aggressive, invasive and highly vascularized. In addition, these tumors consist of large amounts of microglia/macrophages. In previous experiments, we detected an upregulation of CCR2 in microglia/macrophages[for full text, please go to the a.m. URL]<br />66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Subjects :: nervous system
ddc: 610
CCR2
Glioma
Microglia
610 Medical sciences
Medicine

Language :: English
Database :: OpenAIRE
Journal :: 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20150607-20150610; Karlsruhe; DOCDI.03.02 /20150602/
Accession number :: edsair.doi.dedup.....c05220dad83867cebb9adf3f5fdff529
Full Text :: https://doi.org/10.3205/15dgnc106

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