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Non-tuberculous mycobacteria pulmonary disease: an integrated approach beyond antibiotics
- Source :
- ERJ Open Research, Vol 7, Iss 2 (2021), ERJ Open Research, article-version (VoR) Version of Record
- Publication Year :
- 2021
- Publisher :
- European Respiratory Society, 2021.
-
Abstract
- Nontuberculous mycobacterial (NTM) pulmonary disease (PD) is an emerging condition with heterogeneous manifestations from both the microbiological and the clinical point of view. Diagnostic and therapeutic guidelines are available but there are still unmet patients' and physicians' needs, including therapy-related adverse events, symptom control, management of comorbidities, risk of re-exposure to the pathogen and unfavourable outcomes. In the present review, we provide currently available evidence for an integrated approach to NTM-PD beyond antibiotic therapy. This includes 1) avoiding exposure to environments where mycobacteria are present and careful evaluation of lifestyle and habits; 2) implementing a personalised pulmonary rehabilitation plan and airway clearance techniques to improve symptoms, exercise capacity, health-related quality of life (QoL) and functional capacity in daily living activities; 3) a nutritional evaluation and intervention to improve health-related QoL and to control gastrointestinal side-effects during antimicrobial therapy, particularly in those with low body mass index and history of weight loss; and 4) managing comorbidities that affect disease outcomes, including structural lung diseases, immune status evaluation and psychological support when appropriate.<br />An integrated approach, including risk factor prevention, management of comorbidities, nutritional evaluation and intervention and pulmonary rehabilitation, should be considered in the optimal management of nontuberculous mycobacterial pulmonary disease https://bit.ly/2YEqvQg
- Subjects :
- Pulmonary and Respiratory Medicine
medicine.medical_specialty
Activities of daily living
medicine.medical_treatment
MEDLINE
Reviews
03 medical and health sciences
0302 clinical medicine
Quality of life
Weight loss
Intervention (counseling)
Non-tuberculous mycobacteria
medicine
Pulmonary rehabilitation
030212 general & internal medicine
Intensive care medicine
Adverse effect
Lung
business.industry
medicine.anatomical_structure
030228 respiratory system
Medicine
medicine.symptom
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- ERJ Open Research, Vol 7, Iss 2 (2021), ERJ Open Research, article-version (VoR) Version of Record
- Accession number :
- edsair.doi.dedup.....c028bdbb48ab0cf13e310da186a157d2