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From the dilute solution to the pure compound: Extraction strategy based on a multi-stage process of phase separation
From the dilute solution to the pure compound: Extraction strategy based on a multi-stage process of phase separation
- Source :
- SCIENCE CHINA-CHEMISTRY, SCIENCE CHINA-CHEMISTRY, 2010, 53 (9), pp.2070-2076. ⟨10.1007/s11426-010-4074-0⟩
- Publication Year :
- 2010
- Publisher :
- HAL CCSD, 2010.
-
Abstract
- It is very rare that a one-step process of extraction leads to the pure compound with a high degree of purity specified by an industrial application. The various stages of a synthesis process and possible secondary reactions may lead to the synthesis of more or less complex and highly diluted solutions. In this work, the rationale and strategy for extraction and purification of a high added value compound are discussed. All the thinking is based on the knowledge and the exploitation of phase diagrams and then developed for different unit operations of the process. The most significant research tools are the experimental data and the modelling of phase equilibrium to estimate the yield of each step of extraction. The significant example chosen involves all the basic methods of phase separation, starting with liquid-vapour equilibrium: stripping of high volatility components and then more or less complex distillation are classically employed. The theoretical plateau number can be deduced from the equilibrium equation curves. The second step is based on the study of the liquid-liquid equilibrium and is an intermediate step for enrichment of the solution when distillation is not possible. A final step based on solid-liquid equilibrium consists of the selective crystallization of the pure product at low temperature, in order to satisfy the requirements of purity and safety imposed by industrial use. The conclusion includes all isolation operations in the form of a general extraction and purification scheme.
- Subjects :
- 010405 organic chemistry
Chemistry
Thermodynamics
General Chemistry
[CHIM.INOR]Chemical Sciences/Inorganic chemistry
010402 general chemistry
01 natural sciences
0104 chemical sciences
law.invention
Multi stage
Liquid–liquid extraction
law
Azeotropic distillation
Theoretical plate
Crystallization
Distillation
Volatility (chemistry)
ComputingMilieux_MISCELLANEOUS
Phase diagram
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- SCIENCE CHINA-CHEMISTRY, SCIENCE CHINA-CHEMISTRY, 2010, 53 (9), pp.2070-2076. ⟨10.1007/s11426-010-4074-0⟩
- Accession number :
- edsair.doi.dedup.....c0033269fa87d005cf5a5f8092073ae0
- Full Text :
- https://doi.org/10.1007/s11426-010-4074-0⟩