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Niveles de hemoglobina en los que se indica transfundir en el Hospital Universitario Fundación Santa Fe de Bogotá

Authors :
Polanco Bonilla, Lucas German
Suarez Reyes, Gabriel Alexander
Rodríguez Orduz, Jorge Ricardo
Celis Rodríguez, Edgar
Source :
Greer J, Foerster J, Lukens J, al e. Wintrobe´s Clinical Hematology. Segunda ed: Lippincott Williams and Wilkins; 2001, Vincent J, Piagnerelli M. Transfusion in the intensive care unit. Critical Care Medicine. 2006;34(5):S96-S101, Corwin H, Gettinger A, Pearl R, al e. The CRIT study: Anemia and blood transfusion in the critically ill-Current clinical practice in the United States. Critical Care Medicine. 2004;32(1):39-52., Hebert P, Wells G, Blajchman M, al e. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care (TRICC). New England Journal of Medicine. 1999;340(6):409-417., Hoffman R, Benz E, Shattil S, al e. Hematology Basic Principles and Practice. Tercera ed: Elsevier Churchill Livingstone; 2000, Maegele M, Lefering R, Paffrath T, al e. Changes in transfusion practice in multiple injury between 1993 and 2006: a retrospective analysis on 5389 patients from the German Trauma Registry. Transfusion Medicine. 2009;19:117-124, Carson J, Terrin M, Noveck H, al e. Liberal or restrictive transfusion high-risk patients after hip surgery. New England Journal of Medicine. 2011;365, 2453–2462, Vincent J, Baron J, Reinhart K, al e. Anemia and blood transfusion in critically ill patients. JAMA. 2002;288: 1499-1507, Busch M, Kleinman S, Nemo G. Current and emerging infectious risk of blood transfusions. JAMA. 2003;289: 959-962, Raghavan M, Marik P. Anemia, allogenic blood transfusion, and immunomodulation in the critical ill. Chest. 2005;127:295-307, Marik P, Corwin H. Acute lung injury following blood transfusion: expanding the definition. Critical Care Medicine. 2008;36: 3080-3084, Hebert P, Fergusson D, Stather D, al e. Revising transfusion practices in critically ill patients. Critical Care Medicine. 2005;33(1): 7-12, Marik P, Corwin H. Efficacy of RBC transfusion in the critically ill: a systematic review of literatura. Critical Care Medicine. 2008;36:2667-2674, Hebert P, Yetisir E, Martin C, al e. Is a low transfusion threshold safe in critically ill patients with cardiovascular disease? Critical Care Medicine. 2001;29:2700-2703, Choha S, McArdle F, McClelland D, al e. Red cell transfusion practice following the transfusion requirements in critical care study: prospective observational cohort study in a large UK intensive care unit. Vox Sanguinis. 2003;84:211-218, Hebert P, Wells G, Martin C, Tweeddale M, al e. Variation in red cell transfusion practice in the intensive care unit: a multicentre cohort study. Critical Care. 1999;3:57-63, Levy M, Abraham E, Zilberberg M, al e. A descriptive evaluation of transfusion practices in patients receiving mechanical ventilation. Chest. 2005;127:928-935, Corwin H, Parsonnet K, Gettinger A. RBC transfusion in the ICU, Is there a reason? Chest. 1995;108:767-71, Consensus conference. Perioperative red blood cell transfusion. JAMA. 1988;260: 2700-2703, Practice guidelines for blood transfusion and adjuvant therapies. An Update report by the American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Anesthesiology. 2006;105: 198-208, Group EW. Guidelines for red cell and plasma transfusion for adults and children. Canadian Medical Association Journal. 2008;156 (11 suppl.): S1-S24, Andrew R, Duncan W, al e. Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients. British Journal of Haematology. 2013;160: 445–464, Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M. al e. Early goal-directed therapy in the treatment of severe sepsis and septic shock. New England Journal of Medicine. 2001; 345: 1368–1377, Carson J, Duff A, Poses R, Berlin J, Spence R, Trout R, Noveck H, al e. Effect of anaemia and cardiovascular disease on surgical mortality and morbidity. Lancet. 1996; 348, 1055–1060, Londoño J. Metodología de la investigación epidemiológica. Tercera ed: Editorial El Manual Moderno; 2004, Hernández M. Epidemiología, Diseño y Análisis de Estudios: Editorial Médica Panamericana; 2007, Repositorio EdocUR-U. Rosario, Universidad del Rosario, instacron:Universidad del Rosario
Publication Year :
2014
Publisher :
Universidad del Rosario, 2014.

Abstract

Introducción: En los pacientes críticamente enfermos la terapia transfusional es una práctica común. Dentro de los estudios realizados no se han incluido a las ciudades a mayor altura. Este estudio pretende determinar los niveles de hemoglobina sobre los cuales se está transfundiendo a los pacientes en la unidad de cuidados intensivos del Hospital Universitario Fundación Santa Fe de Bogotá a 2600 metros sobre el nivel del mar, para determinar si los niveles de hemoglobina a los que se transfunde a nuestra altura son los óptimos. Métodos: Se realizó un estudio descriptivo retrospectivo, de los pacientes que fueron hospitalizados en la Unidad de Cuidado Intensivo del Hospital Universitario Fundación Santa Fe de Bogotá a partir del 01 de Junio de 2011 y hasta el 31 de Mayo de 2012. Resultados: Del total de los registros analizados el 13,8% de los pacientes presentaron una hemoglobina ≤ 7 y todos fueron transfundidos con glóbulos rojos; y en el rango de 7,1-9 se presentó el mayor porcentaje de transfusión. Se observó que los pacientes con hemoglobina ≤ 7 tienen 18,8 veces mayor riego de fallecimiento, lo que fue estadísticamente significativo (p:0,000). Conclusiones: Encontramos que la terapia transfusional en la unidad de cuidado intensivo, se realiza de acuerdo a recomendaciones dadas por las guías de manejo universalmente aceptadas. Dentro de los resultados de nuestro estudio podemos resaltar una tasa de mortalidad más alta en los pacientes en los cuales se instaura terapia transfusional con un nivel de hemoglobina por debajo de 7g/dl. Introduction: In critically ill patients transfusion therapy is a common practice. Within the studies have not included the cities at higher elevations. This study aims to determine the levels of hemoglobin which is being transfused to patients in the intensive care unit of the University Hospital Foundation Santa Fe de Bogotá at 2600 meters above sea level, to determine whether hemoglobin levels to which transfused to our height are optimal. Methods: A retrospective study of patients who were hospitalized in the Intensive Care Unit of the University Hospital Foundation Santa Fe de Bogotá from June 1, 2011 until May 31, 2012 was performed. Results: Of analyzed records 13.8% of patients had hemoglobin ≤ 7 and all were transfused with red blood cells, and in the range of 7.1 to 9 is the highest percentage of transfusion. It was observed that patients with hemoglobin ≤ 7 are 18,8 times higher risk of death, which was statistically significant (p: 0.000). Conclusions: We found that transfusion therapy in the intensive care unit, is performed according to recommendations given by the management guidelines universally accepted. Among the results of our study we can highlight a higher mortality rate in patients in whom transfusion therapy is established with a hemoglobin level below 7g/dl

Details

Language :
Spanish; Castilian
Database :
OpenAIRE
Journal :
Greer J, Foerster J, Lukens J, al e. Wintrobe´s Clinical Hematology. Segunda ed: Lippincott Williams and Wilkins; 2001, Vincent J, Piagnerelli M. Transfusion in the intensive care unit. Critical Care Medicine. 2006;34(5):S96-S101, Corwin H, Gettinger A, Pearl R, al e. The CRIT study: Anemia and blood transfusion in the critically ill-Current clinical practice in the United States. Critical Care Medicine. 2004;32(1):39-52., Hebert P, Wells G, Blajchman M, al e. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care (TRICC). New England Journal of Medicine. 1999;340(6):409-417., Hoffman R, Benz E, Shattil S, al e. Hematology Basic Principles and Practice. Tercera ed: Elsevier Churchill Livingstone; 2000, Maegele M, Lefering R, Paffrath T, al e. Changes in transfusion practice in multiple injury between 1993 and 2006: a retrospective analysis on 5389 patients from the German Trauma Registry. Transfusion Medicine. 2009;19:117-124, Carson J, Terrin M, Noveck H, al e. Liberal or restrictive transfusion high-risk patients after hip surgery. New England Journal of Medicine. 2011;365, 2453–2462, Vincent J, Baron J, Reinhart K, al e. Anemia and blood transfusion in critically ill patients. JAMA. 2002;288: 1499-1507, Busch M, Kleinman S, Nemo G. Current and emerging infectious risk of blood transfusions. JAMA. 2003;289: 959-962, Raghavan M, Marik P. Anemia, allogenic blood transfusion, and immunomodulation in the critical ill. Chest. 2005;127:295-307, Marik P, Corwin H. Acute lung injury following blood transfusion: expanding the definition. Critical Care Medicine. 2008;36: 3080-3084, Hebert P, Fergusson D, Stather D, al e. Revising transfusion practices in critically ill patients. Critical Care Medicine. 2005;33(1): 7-12, Marik P, Corwin H. Efficacy of RBC transfusion in the critically ill: a systematic review of literatura. Critical Care Medicine. 2008;36:2667-2674, Hebert P, Yetisir E, Martin C, al e. Is a low transfusion threshold safe in critically ill patients with cardiovascular disease? Critical Care Medicine. 2001;29:2700-2703, Choha S, McArdle F, McClelland D, al e. Red cell transfusion practice following the transfusion requirements in critical care study: prospective observational cohort study in a large UK intensive care unit. Vox Sanguinis. 2003;84:211-218, Hebert P, Wells G, Martin C, Tweeddale M, al e. Variation in red cell transfusion practice in the intensive care unit: a multicentre cohort study. Critical Care. 1999;3:57-63, Levy M, Abraham E, Zilberberg M, al e. A descriptive evaluation of transfusion practices in patients receiving mechanical ventilation. Chest. 2005;127:928-935, Corwin H, Parsonnet K, Gettinger A. RBC transfusion in the ICU, Is there a reason? Chest. 1995;108:767-71, Consensus conference. Perioperative red blood cell transfusion. JAMA. 1988;260: 2700-2703, Practice guidelines for blood transfusion and adjuvant therapies. An Update report by the American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Anesthesiology. 2006;105: 198-208, Group EW. Guidelines for red cell and plasma transfusion for adults and children. Canadian Medical Association Journal. 2008;156 (11 suppl.): S1-S24, Andrew R, Duncan W, al e. Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients. British Journal of Haematology. 2013;160: 445–464, Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M. al e. Early goal-directed therapy in the treatment of severe sepsis and septic shock. New England Journal of Medicine. 2001; 345: 1368–1377, Carson J, Duff A, Poses R, Berlin J, Spence R, Trout R, Noveck H, al e. Effect of anaemia and cardiovascular disease on surgical mortality and morbidity. Lancet. 1996; 348, 1055–1060, Londoño J. Metodología de la investigación epidemiológica. Tercera ed: Editorial El Manual Moderno; 2004, Hernández M. Epidemiología, Diseño y Análisis de Estudios: Editorial Médica Panamericana; 2007, Repositorio EdocUR-U. Rosario, Universidad del Rosario, instacron:Universidad del Rosario
Accession number :
edsair.doi.dedup.....bffd10f8548bff80e9980cc5ab1882f4