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The circadian clock system in the mammalian retina
- Source :
- BioEssays. 30:624-633
- Publication Year :
- 2008
- Publisher :
- Wiley, 2008.
-
Abstract
- Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus. This circadian clock is responsible for the temporal organization of a wide variety of functions, ranging from sleep and food intake, to physiological measures such as body temperature, heart rate and hormone release. The retinal circadian clock was the first extra-SCN circadian oscillator to be discovered in mammals and several studies have now demonstrated that many of the physiological, cellular and molecular rhythms that are present within the retina are under the control of a retinal circadian clock, or more likely a network of hierarchically organized circadian clocks that are present within this tissue. BioEssays 30:624-633, 2008. (c) 2008 Wiley Periodicals, Inc.
- Subjects :
- Periodicity
medicine.medical_specialty
Circadian clock
CLOCK Proteins
Biology
Article
Retina
General Biochemistry, Genetics and Molecular Biology
Melatonin
Biological Clocks
Internal medicine
medicine
Animals
Humans
Photoreceptor Cells
Circadian rhythm
Oscillating gene
Feedback, Physiological
Mammals
Sleep in non-human animals
Bacterial circadian rhythms
Circadian Rhythm
Endocrinology
Light effects on circadian rhythm
Trans-Activators
Neuroscience
medicine.drug
Subjects
Details
- ISSN :
- 15211878 and 02659247
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- BioEssays
- Accession number :
- edsair.doi.dedup.....bffbc198d4c9b6cf4ecaec42852d1b4e