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Current results of a multicenter trial in multiple myeloma
- Source :
- Web of Science
- Publication Year :
- 1986
-
Abstract
- 257 untreated myeloma patients (stage II and III) were studied in a multicenter trial. The patients were randomized and received MP or VCMP therapy. No differences in remission rate could be found in both therapy arms. After successful remission induction those patients without maintenance therapy relapsed significantly earlier than those patients receiving maintenance therapy. In pilot studies an etoposide therapy was found ineffective and a multidrug therapy (VBAMDex) could induce high remission rates in high risk and pretreated patients.
- Subjects :
- Oncology
Cancer Research
medicine.medical_specialty
Stage ii
Dexamethasone
Drug Administration Schedule
law.invention
Remission induction
Random Allocation
Maintenance therapy
Randomized controlled trial
law
Multicenter trial
Internal medicine
Antineoplastic Combined Chemotherapy Protocols
medicine
Humans
Cyclophosphamide
Melphalan
Multiple myeloma
Etoposide
Neoplasm Staging
Clinical Trials as Topic
business.industry
Hematology
medicine.disease
Carmustine
Surgery
Doxorubicin
Vincristine
Prednisone
Remission rate
business
Multiple Myeloma
medicine.drug
Subjects
Details
- ISSN :
- 0378584X
- Volume :
- 9
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Onkologie
- Accession number :
- edsair.doi.dedup.....bfeec00d4731195829dce20ed8aedc0e