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Association of the intronic rs2072621 polymorphism of the X-linked GPR50 gene with affective disorder with seasonal pattern

Authors :
M.-F. Poirier
M. Delavest
C. Even
N. Benjemaa
Ralf Jockers
Marie-Odile Krebs
Source :
European Psychiatry. 27:369-371
Publication Year :
2012
Publisher :
Cambridge University Press (CUP), 2012.

Abstract

This case-control study found an association between Seasonal Affective Disorder (SAD) and a single nucleotide polymorphism (intronic rs2072621) of the gene encoding GPR50 (an orphan member of the G protein-coupled melatonin receptor subfamily) in females. This may represent a gender-specific risk factor and a molecular link between melatonin and SAD.

Details

ISSN :
17783585 and 09249338
Volume :
27
Database :
OpenAIRE
Journal :
European Psychiatry
Accession number :
edsair.doi.dedup.....bfea31c44725fb285460fdc52d9f1fd8
Full Text :
https://doi.org/10.1016/j.eurpsy.2011.02.011