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Ancient human mitochondrial genomes from Bronze Age Bulgaria: new insights into the genetic history of Thracians
- Source :
- Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019), Scientific Reports
- Publication Year :
- 2019
- Publisher :
- Nature Publishing Group, 2019.
-
Abstract
- One of the best documented Indo-European civilizations that inhabited Bulgaria is the Thracians, who lasted for more than five millennia and whose origin and relationships with other past and present-day populations are debated among researchers. Here we report 25 new complete mitochondrial genomes of ancient individuals coming from three necropolises located in different regions of Bulgaria – Shekerdja mogila, Gabrova mogila and Bereketska mogila – dated to II-III millennium BC. The identified mtDNA haplogroup composition reflects the mitochondrial variability of Western Eurasia. In particular, within the ancient Eurasian genetic landscape, Thracians locate in an intermediate position between Early Neolithic farmers and Late Neolithic-Bronze Age steppe pastoralists, supporting the scenario that the Balkan region has been a link between Eastern Europe and the Mediterranean since the prehistoric time. Spatial Principal Component Analysis (sPCA) performed on Thracian and modern mtDNA sequences, confirms the pattern highlighted on ancient populations, overall indicating that the maternal gene pool of Thracians reflects their central geographical position at the gateway of Europe.
- Subjects :
- Bronze Age
0301 basic medicine
Mitochondrial DNA
Steppe
Pastoralism
lcsh:Medicine
Ancient history
DNA, Mitochondrial
Article
Genetic history
03 medical and health sciences
0302 clinical medicine
Mitochondrial genome
Phylogenetics
Humans
DNA, Ancient
Bulgaria
lcsh:Science
History, Ancient
Phylogeny
Principal Component Analysis
Multidisciplinary
geography.geographical_feature_category
Ancient DNA
Geography
Genome, Human
lcsh:R
Sequence Analysis, DNA
Genetics, Population
030104 developmental biology
Thracian
Genome, Mitochondrial
mitochondrial variability, Balkan, sPCA
lcsh:Q
Gene pool
030217 neurology & neurosurgery
Human mitochondrial DNA haplogroup
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 9
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....bfdf130a19e819bf99ce3f3971fe18aa