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Differentially expressed miRNAs in retinoblastoma

Authors :
Elio F. Vanin
Marilyn B. Mets
Joshua S. Martin
Nikia A. Laurie
Fabricio F. Costa
Marcelo B. Soares
Joanna Weinstein
Denise M. Scholtens
Paul Bryar
Aunica Jones
Alissa Martin
Source :
Gene. 512:294-299
Publication Year :
2013
Publisher :
Elsevier BV, 2013.

Abstract

MicroRNAs (miRNAs) are short non-coding RNA transcripts that have the ability to regulate the expression of target genes, and have been shown to influence the development of various tumors. The purpose of our study is to identify aberrantly expressed miRNAs in retinoblastoma for the discovery of potential therapeutic targets for this disease, and to gain a greater understanding of the mechanisms driving retinoblastoma progression. We report 41 differentially expressed miRNAs (p

Details

ISSN :
03781119
Volume :
512
Database :
OpenAIRE
Journal :
Gene
Accession number :
edsair.doi.dedup.....bfb420b071522c4a9b9dc88065962751
Full Text :
https://doi.org/10.1016/j.gene.2012.09.129