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Metastatic breast cancer: Who benefits from surgery?
- Source :
- Am J Surg
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- BACKGROUND: We sought to identify characteristics of metastatic breast cancer (MBC) patients who may benefit most from primary tumor resection. METHODS: Recursive partitioning analysis (RPA) was used to categorize non-surgical patients with de novo MBC in the NCDB (2010–2015) into 3 groups (I/II/III) based on 3-year overall survival (OS). After bootstrapping (BS), group-level profiles were applied, and the association of surgery with OS was estimated using Cox proportional hazards models. RESULTS: All patients benefitted from surgery (median OS, surgery vs no surgery): 72.7 vs 42.9 months, 47.3 vs 30.4 months, 23.8 vs 14.4 months (all p
- Subjects :
- Adult
medicine.medical_specialty
Breast surgery
medicine.medical_treatment
Clinical Decision-Making
Breast Neoplasms
Recursive partitioning
Kaplan-Meier Estimate
Risk Assessment
Article
Resection
medicine
Overall survival
Humans
Mastectomy
Aged
Neoplasm Staging
Proportional Hazards Models
Retrospective Studies
Proportional hazards model
business.industry
Patient Selection
General Medicine
Middle Aged
Prognosis
medicine.disease
Metastatic breast cancer
Primary tumor
Surgery
Treatment Outcome
Female
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 00029610
- Volume :
- 223
- Database :
- OpenAIRE
- Journal :
- The American Journal of Surgery
- Accession number :
- edsair.doi.dedup.....bf14e2a67ff9b79962c7e8fec3b2b048