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Exploring the diagnostic value of photoacoustic imaging for breast cancer: the identification of regional photoacoustic signal differences of breast tumors

Authors :
Yuxin Jiang
Changhui Li
Ruojiao Wang
Xujin He
Ruina Zhao
Chenyang Zhao
Meng Yang
Rui Zhang
Lei Zhu
Fang Yang
Lingyi Zhao
Ming Wang
Si-Rui Liu
Jianchu Li
Source :
Biomed Opt Express
Publication Year :
2020

Abstract

We examined 14 benign and 26 malignant breast nodules by a handheld dual-modal PA/US imaging system and analyzed the data using the quantitative and semi-quantitative method. The PA signal spatial density and PA scores of different regions of the benign and malignant nodules were compared, and the diagnostic performances of two diagnostic methods based on PA parameters were evaluated. For both quantitative and semi-quantitative results, significant differences in the distributions of PA signals in different regions of benign and malignant breast lesions were identified. The PA parameters showed good performance in diagnosing breast cancer, indicating the potential of PAI in clinical utilization.

Details

ISSN :
21567085
Volume :
12
Issue :
3
Database :
OpenAIRE
Journal :
Biomedical optics express
Accession number :
edsair.doi.dedup.....bf03800654d4917a143b4ee782571fed