Back to Search
Start Over
Influence of crystalloid and colloid fluid infusion and blood withdrawal on pulmonary bioimpedance in an animal model of mechanical ventilation
- Source :
- Physiological Measurement. 33:1225-1236
- Publication Year :
- 2012
- Publisher :
- IOP Publishing, 2012.
-
Abstract
- Electrical impedance tomography (EIT) is considered useful for monitoring regional ventilation and aeration in intensive-care patients during mechanical ventilation. Changes in their body fluid state modify the electrical properties of lung tissue and may interfere with the EIT measurements of lung aeration. The aim of our study was to assess the effects of crystalloid and colloid infusion and blood withdrawal on bioimpedance determined by EIT in a chest crosssection. Fourteen anaesthetized mechanically ventilated pigs were subjected to interventions affecting the volume state (crystalloid and colloid infusion, blood withdrawal). Six animals received additional crystalloid fluids (fluid group) whereas eight did not (no-fluid group). Global and regional relative impedance changes (RIC, dimensionless unit) were determined by backprojection at endexpiration. Regional ventilation distribution was analyzed by calculating the tidal RIC in the same regions. Colloid infusion led to a significant fall in the global end-expiratory RIC (mean differences: fluid: −91.2, p < 0.001, nofluid: −38.9, p < 0.001), which was partially reversed after blood withdrawal (mean differences, fluid: +45.1, p = 0.047 and no-fluid: +26.2, p = 0.009). The RIC was significantly lower in the animals with additional crystalloids (mean group difference: 45.5, p < 0.001). Global and regional tidal volumes were not significantly affected by the fluid and volume states.
- Subjects :
- Endpoint Determination
Physiology
medicine.medical_treatment
Sus scrofa
Biomedical Engineering
Biophysics
Blood withdrawal
Colloid
Physiology (medical)
Electric Impedance
Tidal Volume
medicine
Animals
Colloids
Infusions, Intravenous
Lung
Electrical impedance tomography
Mechanical ventilation
Body fluid
Blood Specimen Collection
business.industry
Crystalloid Solutions
Respiration, Artificial
medicine.anatomical_structure
Fluid infusion
Anesthesia
Heart Function Tests
Models, Animal
Breathing
Isotonic Solutions
business
Subjects
Details
- ISSN :
- 13616579 and 09673334
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Physiological Measurement
- Accession number :
- edsair.doi.dedup.....beeba3d891e6a1589e56a2a814c9efd9