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Stage-specific difference in timing and pattern of initial recurrence after curative surgery for gastric cancer
- Source :
- Surgical oncology. 30
- Publication Year :
- 2019
-
Abstract
- Background Gastric cancer (GC) follow-up schedule after curative surgery is universally recommended based on the pathologic stage, but their details, including intervals and modalities of surveillance have not yet been standardised. The aim of this study was to investigate the characteristics of GC recurrence by stage to establish optimal postoperative surveillance strategies. Methods Medical information on 5095 patients with GC who underwent curative intent gastrectomy in our institution between January 1989 and December 2013 was reviewed retrospectively. Moreover, 656 patients who had recurrences after radical surgery were identified. Clinicopathologic characteristics, timing and pattern of recurrence, and survival data of these patients were analysed. Results Among the 656 patients, 50 (7.6%), 123 (18.8%), and 483 (73.6%) had stages I, II, and III GC, respectively. The median times to initial recurrence in patients with stages I, II, and III GC were 23.5 months (interquartile range [IQR], 13.0–33.0 months), 13.0 months (IQR, 9.0–25.0 months), and 12.0 months (IQR, 7.0–21.0 months), respectively. In patients with stage I GC, more than half (58%) of them had distant organ metastasis; otherwise, peritoneal dissemination (39%) was the most common pattern in patients with stage III GC. Conclusions Despite the low incidence, the time of initial recurrence in stage I GC was longer than those in stage II and III GC. Moreover, the pattern of initial recurrence was also different according to the pathologic stage. Therefore, clinicians should consider stage-specific differences of recurrence in setting up surveillance strategies after curative surgery for GC patients.
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
medicine.medical_treatment
Adenocarcinoma
Metastasis
03 medical and health sciences
Young Adult
0302 clinical medicine
Interquartile range
Gastrectomy
Stomach Neoplasms
Republic of Korea
medicine
Humans
Neoplasm Invasiveness
Radical surgery
Stage (cooking)
Aged
Neoplasm Staging
Retrospective Studies
Aged, 80 and over
business.industry
Incidence (epidemiology)
Incidence
Cancer
Middle Aged
medicine.disease
Surgery
Survival Rate
Oncology
030220 oncology & carcinogenesis
Lymphatic Metastasis
Curative surgery
030211 gastroenterology & hepatology
Female
Neoplasm Recurrence, Local
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 18793320
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Surgical oncology
- Accession number :
- edsair.doi.dedup.....bee70450407f1ce89746db4c4264ff00