Back to Search Start Over

Rescue therapies for seizure clusters: Pharmacology and target of treatments

Authors :
Barry Gidal
Kamil Detyniecki
Source :
Epilepsia. 63
Publication Year :
2022

Abstract

The primary goal of treatment for seizure clusters is cessation of the cluster to avoid progression to more severe conditions, such as prolonged seizures and status epilepticus. Rescue therapies are key components of treatment plans for patients with seizure clusters. Three rescue therapies are approved in the United States for the treatment of seizure clusters: diazepam rectal gel, midazolam nasal spray, and diazepam nasal spray. This review characterizes the pharmacological function of rescue therapies for seizure clusters, as well as describing γ-aminobutyric acid A (GABA

Details

ISSN :
15281167
Volume :
63
Database :
OpenAIRE
Journal :
Epilepsia
Accession number :
edsair.doi.dedup.....bedd6f525a8d4e4e196a6ef2c004cb49